The Nuffield Department of Surgical Sciences
University of OxfordSenior Principal Investigators
Listings of the Senior Principal Investigators of the Department
Freddie Hamdy
Management of prostate/ bladder cancer; basic/translational research into molecular mechanisms of progression; cancer-induced bone disease; biomarker research
Jonathan M. Austyn
Dendritic cells (DC) of the immune system control many types of immune responses. We are trying to understand how they work, how they react to different chemicals, and how we might be able to use them as vaccines, for example to treat cancer.
Tipu Z. Aziz
Functional neurosurgery for movement disorders and intractable pain, clinical neurophysiology, basic neurophysiology in movement control, brain imaging with MRI and MEG, development of a demand pacemaker for functional neurosurgery
Andrew Bushell
Understanding and harnessing inherent immunological control mechanisms to protect organ transplants from rejection
James V. Byrne
My research is in neurovascular diseases and is focused on improving minimally invasive therapies and diagnostic imaging. I hold joint University and NHS contracts on employment and the research is based on innovation and audits of endovascular treatments as well as collaborative work with other groups in advanced post-processing imaging techniques and blood and CSF flow simulations.
David Cranston
The High Intensity Focussed Ultrasound group was set in 2002 and has close international links with Chongqing in China. The group is currently investigating the treatment of solid tumours at the Churchill Hospital and has close research links with Professor Gail ter Haar, scientific director of the unit and Dr Constantin Coussios in Biomedical engineering.
Claire M. Edwards
Research interests are focused upon the pathogenesis of cancer-induced bone disease, including the contributions of the host bone marrow microenvironment and the role of obesity, adipocytes and adipokines.
Peter John Friend
Isolated organ perfusion and preservation Clinical trials of novel Immunosuppression
Stephen John Golding
High technology imaging applied to cervicofacial disease and Radiological protection.
Derek W.R. Gray
Oxford Consortium for Islet Transplantation, is a multi-disciplinary team that aims to achieve insulin independence in patients with diabetes by transplanting pancreatic islets of Langerhans.
Alexander L. Green
Investigation of autonomic function and pain physiology in human patients undergoing deep brain stimulation
Alison W. Halliday
Large Clinical Trials investigating carotid artery interventions to prevent stroke Carotid Surgery Audit
Linda Hands
1.Use of electronic data transfer in the redesign of patient pathways and care (Telemedicine) 2.Coagulation factors and cytokines in peripheral vascular disease
Paul Johnson
APSPU – The Academic Paediatric Surgery Unit undertakes research ranging from basic laboratory science to evidence-based clinical studies. The principal area of research relates to the endocrine pancreas, and in particular the field of pancreatic islet transplantation for juvenile-onset diabetes; OXCIT – Oxford Consortium for Islet Transplantation, is a multi-disciplinary team that aims to achieve insulin independence in patients with diabetes by transplanting pancreatic islets of Langerhans.
Peter McCulloch
Safety and quality in the delivery of surgical services; Methodology for the evaluation of surgical and interventional techniques and technology; Minimally invasive surgery for gastro-oesophageal cancer
Rutger J. Ploeg
Clinical, translational & experimental research in organ donation and transplantation and focus on mechanisms of injury & repair relevant to enhance donor organ quality, reduce ischaemia-reperfusion injury, improve preservation and allow regeneration after transplantation to increase allograft function and survival.
Kathryn J. Wood
Kathryn Wood is Professor of Immunology in the Nuffield Department of Surgical Sciences, University of Oxford Her research focuses on the immunobiology of cell and organ transplantation
