Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The start of the year saw Nizar Touati join the Transplantation Research Immunology Group (TRIG) directed by Professor Kathryn Wood at the Nuffield Department of Surgical Sciences, as part of a Master of Science traineeship.

During the six month placement, Nizar, who is a medical student at the University of Paris Pierre and Marie Curie, is working alongside Postdoctoral Scientist Dr Joanna Hester on a research project studying the molecular and cellular abilities of regulatory T cells (Tregs) to modulate immune responses and in particular evaluate their role in rejection of transplanted organs.

From a clinical translation perspective using Treg cell therapy for the organ transplantation, the team is trying to understand better how Treg cells are able to induce tolerance to donor antigens among transplanted patients, in order to improve significantly their quality of life and long term graft survival.

Nizar comments: ‘I am really interested in the immune mechanisms underlying tolerance and rejection of transplanted organs and I am trying to better understand the molecular and cellular interactions between effector immune cells and T regulatory cells in the particular context of a graft microenvironment.

‘TRIG is a perfect laboratory to undertake a research project and to fully focus on it. Oxford is a really nice place to work and to do research.’

He continues: ‘I really think that research is essential to make progress in medicine and that they are complementary to each other. That is why I am performing a double programme allowing me to learn and to do both research and medicine.’

Learn more about the work of TRIG.

Similar stories

Latest issue of JNDS now online

Department Publication

The latest issue of the Journal of the Nuffield Department of Surgical Sciences (JNDS) is now available to read.

New Cochrane evidence explores treatment options for chronic ear disease

Publication Research

A new Evidently Cochrane blog post for World Hearing Day summarises seven recent reviews on medical treatments for infection and inflammation of the middle ear.

New reporting guidelines to bridge the gap from development to implementation in clinical artificial intelligence

Innovation Research

In a correspondence to Nature Medicine, a team of Oxford-led academics describe upcoming new guidelines to improve the reporting of early clinical stage (or first-with-human) evaluation of decision support systems driven by artificial intelligence.

Cochrane ENT awarded NIHR funding for COVID-19 project

Awards and appointments Coronavirus COVID-19 Research

Cochrane ENT at the Nuffield Department of Surgical Sciences has been awarded funding by the National Institute for Health Research (NIHR) to complete a suite of living systematic reviews investigating the effectiveness and safety of interventions to prevent and treat loss of smell after COVID-19 infection.

JNDS: new issue out now

Department Publication

Journal of the Nuffield Department of Surgical Sciences (JNDS) has published its next issue, featuring top case reports written by University of Oxford medical students during their clinical studies.

First peer-reviewed results of phase 3 human trials of Oxford coronavirus vaccine demonstrate efficacy

Coronavirus COVID-19 Publication Research

Today University of Oxford and AstraZeneca researchers present a pooled analysis of Phase 3 trials of a vaccine against SARS-CoV-2 across two different dose regimens, resulting in an average efficacy of 70.4%.