Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

© 2016 Elsevier Ltd All rights reserved. Transplantation has revolutionized the treatment of organ failure but remains limited by the challenge of controlling alloresponses to the organ transplant. Central to addressing this challenge is understanding the nature of the immune response and developing safer methods for its control. In vivo models are critical to this goal as they facilitate investigation of novel therapies in the context of a complete immune system. This article details the various transplantation animal models and their merits and limitations.

Original publication

DOI

10.1016/B978-0-12-374279-7.15017-9

Type

Chapter

Book title

Encyclopedia of Immunobiology

Publication Date

27/04/2016

Volume

5

Pages

270 - 274