Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

© 2018 by Taylor & Francis Group, LLC. Congenital hyperinsulinism (CHI), previously termed persistent hyperinsulinemic hyperglycemia of infancy (PHHI), is a spectrum of conditions characterized by profound hypoglycemia in the presence of inappropriately high insulin secretion.1 2 Although rare overall, CHI is a significant cause of hypoglycaemic brain injury in the newborn1 and subsequent mental retardation,3 and therefore, all those involved in the medical and surgical management of neonates need to be familiar with this condition so that the diagnosis can be made promptly, and early treatment implemented. This chapter provides an overview of the etiology, clinical presentation, diagnosis, and management of CHI to facilitate this.

Original publication

DOI

10.4324/9781315113968

Type

Chapter

Book title

Newborn Surgery, Fourth Edition

Publication Date

01/01/2017

Pages

591 - 596