Location
Radiobiology Research Institute, Churchill Hospital, Headington, Oxford
Research groups
Collaborators
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Ian Mills
John Black Associate Professor of Prostate Cancer and Deputy Head of Department
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Clare Verrill
Associate Professor
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Alastair Lamb
Cancer Research UK Clinician Scientist
Ashwin Nandakumar
BSc, PhD
Postdoctoral Scientist
My research focuses on understanding the insulin-like growth factor (IGF) axis in prostate cancer.
Aberrant IGF signalling is known to contribute to the growth and progression of various cancers. People with high blood circulating IGF-1 levels are at an increased risk of developing cancers of the prostate, colon, lung and breast. Conversely, subjects with deficiencies in IGF-1 production are protected from developing cancers. My research aims to investigate how high circulating IGF-1 could influence cancer risk by regulating components of the tumour microenvironment.
I recently completed my DPhil (PhD) in Oncology with Val Macaulay in the Department of Oncology at the University of Oxford. Prior to this, I completed my BSc (Hons) in Biomedical Science at Kingston University, London.
Recent publications
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Targeting IGF Perturbs Global Replication through Ribonucleotide Reductase Dysfunction.
Journal article
Rieunier G. et al, (2021), Cancer Res, 81, 2128 - 2141