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MSc START DATE

September 2019

PROJECT TITLE

Assessment of the pancreas during preservation using oxygenated hypothermic machine perfusion

SUPERVISORS

Professor Peter Friend and Dr Julien Branchereau

Gabriella Hakim

BSc (Hons) Biomedical Sciences, UCL.


MSc (Res) student

  • CEO and Co-founder of VacTrack

I am currently a second year MSc by Research student within the Ploeg research group. The objective of this study is to establish the modalities of an innovative technique for the preservation of pancreatic transplants on a pulsatile hypothermic perfusion machine (HMP) and to compare SCS, HMP and Hypothermic Oxygenated Pulsatile Perfusion (HOPE) preservation methods for pancreas in a Donation after Cardiac Death (DCD) porcine model. The current standard technique for preserving transplants after removal and before transplantation remains static cold storage (SCS). Changes in donor characteristics have led transplant teams to consider increasingly fragile pancreases, which are even more susceptible to ischemia reperfusion injury. 

I obtained a degree in Biomedical Sciences at UCL, where I did an extended writing project on Type I Diabetes and Simultaneous Pancreas Kidney Transplantation. My dissertation was focused on fertility, looking at Reactive Oxygen species as a predictor for embryonic development. The field of transplantation really attracted me and therefore I applied to this programme in order to develop my knowledge on transplantation, especially the pancreas. In 2020, I also co-founded VacTrack, a digital patient-centric platform that offers seamless vaccine tracking and guidance, as well as testing capabilities. 

Publications

Modèle préclinique de perfusion normothermique ex situ de transplants pancréatiques 

G Hakim, et al. 

ScienceDirect 2020 November 3.