loCATIONS

Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), Churchill Hospital, Oxford OX3 7LE

Nicholas Magrane

Research Technician

I joined the Islet Transplantation team as a Technician in January 2020 after graduating with an MSci in Neuroscience from University College London in 2019. 

Our group receives pancreases from deceased donors and isolates the islets, which contain the insulin-producing cells. The islets are then transplanted into type 1 diabetes patients suffering from hypoglycaemia unawareness and severe, potentially lethal, hypoglycaemic events with the aim of restoring hypoglycaemia awareness and thereby preventing future hypoglycaemic events.

In addition to my role in islet isolation, I am involved in research to improve the efficacy of islet transplantation by investigating ways to improve the survival of islets once they have been transplanted into patients.