MSci (Hons), PhD
My research focuses on the breakdown of the extracellular matrix during islet isolation. I investigate how specific enzymes digest the islet-exocrine interface in order to release islets, particularly with respect to donor characteristics such as age and BMI. By tailoring the enzymes to the donor organ, this may result in improved pancreatic islet cell yield. Subsequently, this would allow a greater transplantation rate and treatment of patients with type 1 diabetes.
I am also an active member of the clinical islet isolation team so my research directly translates into medical application.