My research focuses on exploration of underlying brain function related to pain and its modulation. Pain, in particular chronic pain, is one of the most serious health issues and it causes suffering worldwide. Through my work, I aim to understand underlying neurophysiology in chronic pain and analgesia through advanced neurophysiological approaches and neuromodulation techniques. Recently, by using local field potentials (LFP) recorded from patients with chronic pain undergoing deep brain stimulation (DBS), we were able to show how neural oscillations in sensory thalamus contribute to pain relief. I am also interested in the function of thalamocortical networks in pain perception and pain modulation.
My critical goal is to understand the mechanism of neural circuits related to pain perception and its modulation and further help to relieve human suffering.
Characteristics of local field potentials correlate with pain relief by deep brain stimulation.
Huang Y. et al, (2016), Clin Neurophysiol, 127, 2573 - 2580
Measuring complex behaviors of local oscillatory networks in deep brain local field potentials.
Huang Y. et al, (2016), J Neurosci Methods, 264, 25 - 32
Characteristics of thalamic local field potentials in patients with disorders of consciousness.
Huang Y. et al, (2015), Conf Proc IEEE Eng Med Biol Soc, 2015, 3779 - 3782
Tremor dependant nonlinear interaction in deep brain local field potentials of Parkinson's disease
Wang Z. et al, (2014), Proceedings - 2014 7th International Conference on BioMedical Engineering and Informatics, BMEI 2014, 399 - 404