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Using a specific antibody, we found that expression of the viral restriction factor IFITM3 differs across cell types within the immune compartment with higher expression in myeloid rather than lymphoid cells. IFITM3 expression was increased following IFN stimulation, mostly type I, in immune cells, with the exception of T cells.

Original publication

DOI

10.1002/eji.202048706

Type

Journal article

Journal

Eur J Immunol

Publication Date

03/2021

Volume

51

Pages

742 - 745

Keywords

IFITM3, IFN, innate immunity, myeloid cells, viral restriction