Using a specific antibody, we found that expression of the viral restriction factor IFITM3 differs across cell types within the immune compartment with higher expression in myeloid rather than lymphoid cells. IFITM3 expression was increased following IFN stimulation, mostly type I, in immune cells, with the exception of T cells.
Journal article
Eur J Immunol
03/2021
51
742 - 745
IFITM3, IFN, innate immunity, myeloid cells, viral restriction, A549 Cells, Antiviral Agents, CD4-Positive T-Lymphocytes, Cell Line, Cell Line, Tumor, HEK293 Cells, Humans, Interferon Type I, Lymphocytes, Membrane Proteins, RNA-Binding Proteins