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Prostate cancer risk stratification using single-nucleotide polymorphisms (SNPs) demonstrates considerable promise in men of European, Asian, and African genetic ancestries, but there is still need for increased accuracy. We evaluated whether including additional SNPs in a prostate cancer polygenic hazard score (PHS) would improve associations with clinically significant prostate cancer in multi-ancestry datasets.

Original publication

DOI

10.1038/s41391-022-00497-7

Type

Journal article

Journal

Prostate Cancer and Prostatic Diseases

Publication Date

12/02/2022