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BACKGROUND: Living kidney donation risk is likely to differ according to donor's demographics. We aimed to analyse the effects of age, sex, body mass index (BMI) and ethnicity. METHODS: A systematic review and meta-analysis was undertaken of the effects of preoperative patient characteristics on donor kidney function outcomes, surgical complications, and hypertension. RESULTS: 5129 studies were identified, of which 31 met the inclusion criteria, mainly from the USA and Europe. The estimated glomerular filtration rate (eGFR) in donors aged over 60 years was a mean of 9.54 ml per min per 1.73 m2 lower than that of younger donors (P 

Original publication




Journal article


Br J Surg

Publication Date





671 - 678


Aged, Female, Glomerular Filtration Rate, Humans, Hypertension, Kidney, Kidney Failure, Chronic, Kidney Transplantation, Living Donors, Male, Nephrectomy, Obesity, Retrospective Studies, Time Factors