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Mesenchymal stem cells (MSCs) are known to be capable of suppressing immune responses and offer therapeutic potential for achieving transplantation tolerance. This review will discuss the impacts of MSCs on transplant immunity and focus on the potential role of MSCs in protecting islet grafts from both rejection and autoimmune attack.

Original publication

DOI

10.1097/TP.0b013e3181c6ffbe

Type

Journal article

Journal

Transplantation

Publication Date

15/02/2010

Volume

89

Pages

270 - 273

Keywords

Bone Marrow Transplantation, Child, Diabetes Mellitus, Type 1, Graft Rejection, Humans, Immunosuppression, Incidence, Islets of Langerhans, Islets of Langerhans Transplantation, Mesenchymal Stem Cell Transplantation, Mesenchymal Stromal Cells, Transplantation, Homologous