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T Regulatory cells (Treg) play an important role in the induction and maintenance of immunological tolerance to self and alloantigens. Recent findings in experimental transplant models have demonstrated that Treg can control acute and delayed allograft rejection. Preclinical attempts to use Treg as a cellular therapy have been successfully undertaken demonstrating the safety and feasibility of such treatment, suggesting that they have therapeutic potential. © 2011 by Elsevier Inc. All rights reserved.

Original publication

DOI

10.1016/j.transproceed.2011.06.050

Type

Journal article

Journal

Transplantation Proceedings

Publication Date

01/07/2011

Volume

43

Pages

2135 - 2136