Contraceptive strategies for reducing the risk of reproductive cancers
Aliabadi AR., Wilailak S., McNally O., Berek JS., Sridhar A., Sheffield J., Kasliwal A., Musinguzi J., González CC., Ahsan A., Mola G., Roy P., Lam WC., Serrano MAG., Askew I., Ten Hoope-Bender P., Tyson N., Townsend J., Makins A., Fuchs-Montgomery N., Cobley B., Kehoe S., Pomerantz T., Lindeque G., Anorlu R., Scambia G., Okamoto A., Schmalfeldt B., Pareja R., Creutzberg C., Mutch D., Matias-Guiu X., Fotopoulou C.
Reproductive cancers, encompassing various malignancies like endometrial, ovarian, cervical cancer, and gestational trophoblastic neoplasia, pose a significant global health burden. Understanding their patterns is vital for effective prevention and management. Contraceptives show a protective effect against some of these cancers. This clinical guidance document aims to elucidate the disease burden of reproductive cancers and the evidence supporting contraceptive methods in prevention and management. Regional disparities in incidence and mortality highlight the urgent need for targeted interventions, particularly in low-resource settings. Healthcare providers must weigh individual risk profiles and medical eligibility criteria when discussing contraceptive options. Enhanced health literacy through direct patient education is essential for leveraging low-cost behavioral interventions to mitigate reproductive cancer risks.