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Isoliquiritigenin [ILG, (E)-1] was readily prepared via the Horner-Wadsworth-Emmons reactions using β-ketophosphonates 5a, b. An improved protocol for the synthesis of (E)-1 via the Claisen-Schmidt condensation was also presented.

Type

Journal article

Journal

Chem Pharm Bull (Tokyo)

Publication Date

2011

Volume

59

Pages

885 - 888

Keywords

Chalcones, Stearic Acids, Stereoisomerism