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In this chapter, we describe the history of transplantation, the multiple cell types, and mechanisms that are involved in rejection and tolerance of a transplanted organ, as well as summarize the common and promising new therapeutics used in transplant patients.

Original publication

DOI

10.1007/978-1-4939-8938-6_12

Type

Journal article

Journal

Methods Mol Biol

Publication Date

2019

Volume

1899

Pages

159 - 180

Keywords

B cells, Cell therapy, Clinical symptoms of rejection, Immune mechanisms of rejection, Immunosuppression, Organ transplant, Regulatory cells, T cells, Transplant tolerance