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Search results (91)

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A Phase Ib/II study of IGF-neutralising antibody xentuzumab with enzalutamide in metastatic castration-resistant prostate cancer.

Macaulay VM. et al, (2023), Br J Cancer, 129, 965 - 973

GeneFEAST: the pivotal, gene-centric step in functional enrichment analysis interpretation

TAYLOR A., (2023)

WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma.

Coupe N. et al, (2023), Cell Oncol (Dordr), 46, 391 - 407

CHK1 inhibition exacerbates replication stress induced by IGF blockade.

Wu X. et al, (2022), Oncogene, 41, 476 - 488

CHK1 inhibition exacerbates replication stress induced by IGF blockade

Macaulay V. et al, (2021), Oncogene

IGF-1R nuclear import and recruitment to chromatin involves both alpha and beta subunits.

Mills JV. et al, (2021), Discov Oncol, 12

Targeting IGF Perturbs Global Replication through Ribonucleotide Reductase Dysfunction.

Rieunier G. et al, (2021), Cancer Res, 81, 2128 - 2141

IGF-1R nuclear import and recruitment to chromatin involves both alpha and beta subunits.

Mills JV. et al, (2021), Discov Oncol, 12

IGF targeting perturbs global replication through ribonucleotide reductase dysfunction.

RIEUNIER G. et al, (2020), BioRxiv

Type 1 IGF receptor associates with adverse outcome and cellular radioresistance in paediatric high-grade glioma.

Simpson AD. et al, (2020), Br J Cancer, 122, 624 - 629

Dual-specificity protein phosphatase DUSP4 regulates response to MEK inhibition in BRAF wild-type melanoma.

Gupta A. et al, (2020), Br J Cancer, 122, 506 - 516

Radioresistant laryngeal cancers upregulate type 1 IGF receptor and exhibit increased cellular dependence on IGF and EGF signalling.

Qureishi A. et al, (2019), Clin Otolaryngol, 44, 1026 - 1036

Therapeutic Targeting of the IGF Axis.

Osher E. and Macaulay VM., (2019), Cells, 8

Increased EZH2 expression in prostate cancer is associated with metastatic recurrence following external beam radiotherapy.

Wu X. et al, (2019), Prostate, 79, 1079 - 1089

Bad to the Bone: The Role of the Insulin-Like Growth Factor Axis in Osseous Metastasis.

Rieunier G. et al, (2019), Clin Cancer Res, 25, 3479 - 3485

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