Search results

Genetic mapping of tumours reveals how cancers grow

Publication Research

11 August 2022

Researchers from the University of Oxford, KTH Royal Institute of Technology, Science for Life Laboratory, and the Karolinska Institutet, Solna, Sweden, have found that individual prostate tumours contain a previously unknown range of genetic variation.

Two NDS researchers receive prestigious MRC Clinical Research Training Fellowships

Awards and appointments Graduate studies Research

22 July 2022

Miss Catherine Lovegrove and Dr Alexander Sagar from the Nuffield Department of Surgical Sciences (NDS) have been awarded highly competitive Clinical Research Training Fellowships by the Medical Research Council (MRC).

WHO Classification of Tumours programme awarded large grant to improve classification and evidence base

Awards and appointments Research

8 July 2022

A new project titled Mapping the Evidence for the World Health Organization (WHO) Classification of Tumours: A Living Evidence Gap Map by Tumour Type (WCT EVI MAP), led by researchers of the WHO Classification of Tumours programme at the International Agency for Research on Cancer (IARC), has received a grant of €3.5 million from the European Commission. This four-year project, which will be undertaken in collaboration with six other international institutions, including Oxford University's Nuffield Department of Surgical Sciences (NDS), was launched on 1 July 2022.

Oxford's largest ever study into varicose veins shows need for surgery is linked to genetics

Publication Research

14 June 2022

Varicose veins are a very common manifestation of chronic venous disease, affecting over 30% of the population in Western countries. In America, chronic venous disease affects over 11 million men and 22 million women aged 40–80 years old. Left untreated it can escalate to multiple health complications including leg ulcers and ultimately amputations. A new international study by Oxford researchers published on 2 June 2022 in Nature Communications establishes for the first time, a critical genetic risk score to predict the likelihood of patients suffering with varicose veins to require surgery, as well as pointing the way towards potential new therapies.

New reporting guidelines developed to improve AI in healthcare settings

Publication Research

19 May 2022

New reporting guidelines, jointly published in Nature Medicine and the BMJ by Oxford researchers, will ensure that early studies on using Artificial Intelligence (AI) to treat real patients will give researchers the information needed to develop AI systems safely and effectively.

Results of the REF 2021: congratulations and thank you

Department Research

12 May 2022

Today, the UK funding bodies have published the results of the UK’s most recent national research assessment exercise, the Research Excellence Framework (REF) 2021.

NDS projects awarded CRUK Oxford Cancer Development Fund

Awards and appointments Research

10 May 2022

Two research projects at the Nuffield Department of Surgical Sciences (NDS) have been awarded pump-prime funding from this year’s CRUK Oxford Centre Development Fund.

Study finds higher risk of all-cause mortality among paediatric cancer patients in LMICs during the pandemic

Publication Research

13 April 2022

During the first nine months of the COVID-19 pandemic, paediatric cancer patients from lower- and middle-income countries (LMICs) faced a higher risk of all-cause mortality than those in high-income countries, according to an international study led by the University of Oxford.

Study reveals that bone changes energy requirements of cancer cells to promote growth and survival

Publication Research Women

11 March 2022

Interrogating metabolic cross-talk in the tumour-bone microenvironment, new research from the Edwards Group shows how the pentose phosphate pathway contributes to prostate cancer bone metastasis.

First-in-human implant of a “closed-loop” bioelectronic research system for investigating treatments for brain disorders

Research

7 February 2022

Researchers at Oxford University have implanted a novel closed-loop research platform for investigating the role of the pedunculopontine nucleus (PPN) – a brainstem nucleus – in Parkinson’s-like Multiple Systems Atrophy (MSA).

FDA approves novel organ preservation device developed across Biomedical Engineering and Surgery

Research

4 January 2022

First therapeutic device developed within the Institute of Biomedical Engineering (IBME) and the Nuffield Department of Surgical Sciences (NDS) completes regulatory approval on both sides of the Atlantic.

Oxford team publish blueprint for making millions of doses of a new vaccine within 100 days

Coronavirus COVID-19 Research

21 December 2021

The University of Oxford’s vaccine manufacturing research team has today published a pre-print paper demonstrating the feasibility of a step change in the speed and volume of production of adenovirus-vectored vaccines against new virus variants or other future pandemics.

Dr Matthew Bottomley wins Stewart Cameron Science Award

Awards and appointments Research

9 December 2021

Congratulations to Dr Matthew Bottomley, who has been announced as the joint winner of the Stewart Cameron Science Award by the Royal Society of Medicine (RSM).

Clare Verrill receives Turing Fellowship

Awards and appointments Research Women

1 October 2021

Thirty-three University of Oxford researchers have been named Turing Fellows for the 2021/22 academic year, including Associate Professor Clare Verrill from the Nuffield Department of Surgical Sciences (NDS).

Researchers awarded Wellcome Innovator Grant to investigate role of brainstem nucleus in human consciousness

Awards and appointments Innovation Research

30 September 2021

Researchers at Oxford University have received a prestigious Wellcome Innovator Grant for investigating the role of the pedunculopontine nucleus (PPN) – a brainstem nucleus – in human consciousness.

Discovered gene patterns can predict prostate cancer treatment response

Publication Research

17 September 2021

Nearly 40,000 men are diagnosed with prostate cancer each year in the UK. Perhaps the most significant clinical challenge today is deciding which type of treatment will work best for different patient groups.

Regent Lee wins top UKRI Future Leaders Fellowship

Awards and appointments Research

8 September 2021

Dr Regent Lee of the Nuffield Department of Surgical Sciences is one of eight Oxford University academics who have been awarded significant financial funding from the UK Research and Innovation’s (UKRI) Future Leaders Fellowships Scheme.

Largest trial of carotid artery surgery and stenting finds similar long-term effects on stroke risk

Publication Research Women

30 August 2021

Results from a major clinical trial demonstrate that both stenting and surgery are low-risk and similarly effective procedures for treating carotid artery disease.

Chan Zuckerberg Initiative awards funds to Paul Johnson for paediatric research

Awards and appointments Research

27 August 2021

New Cochrane evidence highlights uncertainty about the interventions used to prevent and treat loss of smell after COVID-19 infection

Coronavirus COVID-19 Publication Research

3 August 2021

Cochrane ENT at the Nuffield Department of Surgical Sciences has published two systematic reviews investigating the effectiveness and safety of interventions to prevent and treat loss of smell following COVID-19 infection.