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« Back to NewsOxford's largest ever study into varicose veins shows need for surgery is linked to genetics
14 June 2022
Varicose veins are a very common manifestation of chronic venous disease, affecting over 30% of the population in Western countries. In America, chronic venous disease affects over 11 million men and 22 million women aged 40–80 years old. Left untreated it can escalate to multiple health complications including leg ulcers and ultimately amputations. A new international study by Oxford researchers published on 2 June 2022 in Nature Communications establishes for the first time, a critical genetic risk score to predict the likelihood of patients suffering with varicose veins to require surgery, as well as pointing the way towards potential new therapies.
New reporting guidelines developed to improve AI in healthcare settings
19 May 2022
New reporting guidelines, jointly published in Nature Medicine and the BMJ by Oxford researchers, will ensure that early studies on using Artificial Intelligence (AI) to treat real patients will give researchers the information needed to develop AI systems safely and effectively.
Study finds higher risk of all-cause mortality among paediatric cancer patients in LMICs during the pandemic
13 April 2022
During the first nine months of the COVID-19 pandemic, paediatric cancer patients from lower- and middle-income countries (LMICs) faced a higher risk of all-cause mortality than those in high-income countries, according to an international study led by the University of Oxford.
Automated assessment of pathology image quality
6 April 2022
The new Oxford-developed artificial intelligence tool PathProfiler automates the quality control of large retrospective pathology image datasets to increase their usability in downstream research.
Study reveals that bone changes energy requirements of cancer cells to promote growth and survival
11 March 2022
Interrogating metabolic cross-talk in the tumour-bone microenvironment, new research from the Edwards Group shows how the pentose phosphate pathway contributes to prostate cancer bone metastasis.
Special issue of JNDS published
24 November 2021
Journal of the Nuffield Department of Surgical Sciences (JNDS) has published a new special issue, featuring highlights from the 2021 NDS Virtual Research Away Day.
Discovered gene patterns can predict prostate cancer treatment response
17 September 2021
Nearly 40,000 men are diagnosed with prostate cancer each year in the UK. Perhaps the most significant clinical challenge today is deciding which type of treatment will work best for different patient groups.
Largest trial of carotid artery surgery and stenting finds similar long-term effects on stroke risk
30 August 2021
Results from a major clinical trial demonstrate that both stenting and surgery are low-risk and similarly effective procedures for treating carotid artery disease.
New issue of JNDS now online
16 August 2021
A new issue of the Journal of the Nuffield Department of Surgical Sciences (JNDS) has been published.
New Cochrane evidence highlights uncertainty about the interventions used to prevent and treat loss of smell after COVID-19 infection
3 August 2021
Coronavirus COVID-19 Publication Research
Cochrane ENT at the Nuffield Department of Surgical Sciences has published two systematic reviews investigating the effectiveness and safety of interventions to prevent and treat loss of smell following COVID-19 infection.
Potential for radiotherapy and VTP multimodality therapy for prostate cancer
21 June 2021
A recent collaborative study from the University of Oxford has investigated the potential benefit of a combined therapy approach to prostate cancer treatment, using radiotherapy and vascular targeted photodynamic therapy (VTP), which could lead to first-in-man early phase clinical trials.
Artificial intelligence tool for streamlining pathology workflow
26 May 2021
Clinical Publication Research Women
A multidisciplinary team, comprising Andrea Chatrian, Dr Richard Colling, Professor Clare Verrill, Professor Jens Rittscher and colleagues, develops an algorithm for automated requesting of additional investigation in diagnostically uncertain prostate biopsies.
Latest issue of JNDS now online
20 April 2021
The latest issue of the Journal of the Nuffield Department of Surgical Sciences (JNDS) is now available to read.
New Cochrane evidence explores treatment options for chronic ear disease
3 March 2021
A new Evidently Cochrane blog post for World Hearing Day summarises seven recent reviews on medical treatments for infection and inflammation of the middle ear.
JNDS: new issue out now
11 December 2020
Journal of the Nuffield Department of Surgical Sciences (JNDS) has published its next issue, featuring top case reports written by University of Oxford medical students during their clinical studies.
First peer-reviewed results of phase 3 human trials of Oxford coronavirus vaccine demonstrate efficacy
8 December 2020
Coronavirus COVID-19 Publication Research
Today University of Oxford and AstraZeneca researchers present a pooled analysis of Phase 3 trials of a vaccine against SARS-CoV-2 across two different dose regimens, resulting in an average efficacy of 70.4%.
Transplant kidney survival rate improves with new method of transportation
20 November 2020
New research by the Consortium for Organ Preservation in Europe (COPE) has found that a new method to transport donor kidneys, which uses a combination of cold perfusion with oxygen, can significantly improve transplant results, with less graft failure, better function and lower rejection of the kidney when compared to cold perfusion alone. For patients who need a kidney transplant this is a big step forward. The study, carried out in Belgium, The Netherlands and the UK, was published today in The Lancet.
Race, science and (im)precision medicine
26 October 2020
Congratulations to George Adigbli, a DPhil student in the Transplantation Research and Immunology Group at the Nuffield Department of Surgical Sciences, whose article on the limitations of using race in biomedicine has been published this month in Nature Medicine.
Fourth issue of JNDS published
9 July 2020
Journal of the Nuffield Department of Surgical Sciences (JNDS) has published its fourth issue.
New issue of JNDS published
16 April 2020
Journal of the Nuffield Department of Surgical Sciences (JNDS) has published its third issue.