Professor Paul Johnson from the Nuffield Department of Surgical Sciences and the Director of the Oxford Islet Transplant programme, together with Professor Alison Simmons, the Director of the Oxford University MRC Human Immunology Unit (MRC HIU), and Dr Hashem Koohy, group leader at Radcliffe Department of Medicine and the MRC HIU, have been awarded a Chan Zuckerberg Initiative Paediatric Networks for the Human Cell Atlas grant.
The Chan Zuckerberg Initiative (CZI) has announced $33 million in grants to support collaborative groups of researchers and paediatricians to better understand, prevent, and treat childhood diseases.
These 17 groups of researchers represent 15 different countries, and will contribute healthy paediatric single-cell reference data to the global Human Cell Atlas as a foundational resource for providing insight into the cellular origins of disease onset in children.
The Oxford team's project aims to develop an open access spatiotemporal atlas of childhood intestinal development, with the team building a single-cell atlas of the paediatric intestine. This will help researchers and clinicians understand how the human intestine matures in childhood, as well as adult intestinal diseases.