Currently, less than 5% of government funding for medical research goes into surgery
One of only nine Royal College of Surgeons specialist trial centres across the whole of the UK, SITU is a collaboration between the Nuffield Department of Surgical Sciences (NDS) and the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS). We have an extensive portfolio of surgical trials and welcome expressions of interest from potential new researchers.
More information about NDS SITU and our work within surgical research can be found by following the links below.
About Us
Our Surgical Trials
Work With Us
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NDS SITU Mission Statement |
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NDS SITU Core Principle |
| We design, develop, and deliver high quality, innovative and impactful surgical trials using novel methodologies and technologies to shape the future of trial-based research and pave the way for evolution in clinical practice. | We have established a nurturing environment that promotes continuous learning and development for all of our staff and collaborators, and together we have an unfaltering dedication to implementing meaningful improvements in patient care and experience. |
The NDS SITU team
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Sheraz Markar
Professor of Upper Gastrointestinal Surgery and Director of NDS SITU
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Michael Douek
Professor of Surgical Sciences & Breast Cancer, Academic Director of NDS SITU
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Charles Malyon
Clinical Trial Manager
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Alice Guazzelli
Clinical Trial Manager
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Melody Chin
Clinical Trial Manager - DISCUS
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Laura Lloyd Jones
Clinical Data Manager
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Martyn Hill
Statistician
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Alison Horne
Data Manager
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James Silver
Clinical Trial Coordinator
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Sarah Crosweller
Clinical Trial Manager
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Sian Saul
Clinical Data Manager
Latest News
The NIHR recently interviewed Rachel Rolph, Chief Investigator of the Restore-B trial into whether mesh should be used in breast reconstruction after surgery for breast cancer. Read the Q&A.
Latest publications
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The cingulum: anatomy, connectivity and what goes beyond
Journal article
Kollenburg L. et al, (2025), Brain Communications
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Deep Brain Stimulation (DBS) and Motor Cortex Stimulation (MCS) for Central Post-Stroke Pain: A Systematic Review And Meta-Analysis.
Journal article
Kannan S. et al, (2025), Pain Med
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Homozygous DNAJC6 Mutated Juvenile Onset Dystonia-Parkinsonism Is Responsive to Pallidal Deep Brain Stimulation.
Journal article
Manfield J. et al, (2024), Mov Disord Clin Pract
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Safety and efficacy of different transplant kidney biopsy techniques: comparison of two different coaxial techniques and needle types.
Journal article
Li D. et al, (2024), Abdom Radiol (NY)