BSc (Hons) PhD PGCE
Operational Lead NDS SITU
I am Operational Lead for NDS SITU, overseeing a portfolio of surgical clinical trials in the areas of urology (PROMOTE, PART and TRANSLATE), Transplant (NKP-1, TWO and SENTINEL), cardiology (ART) breast cancer (ENDONET), and device trials in ophthalmology and deep brain stimulation. I oversee the portfolio with Amy Taylor and work closely with the director of SITU, Michael Douek, and the deputy directors, Richard Bryant, Sheraz Markar and Alex Green.
I am involved in the development of new grant applications, the setting up of new trials and provide ongoing management and guidance to trials at all stages. I am responsible for helping the trial managers meet their trial milestones and work closely with the trial CIs to ensure trials are delivered to a high standard.
I have been in research for over two decades. I hold an honours degree in neuroscience and a PhD in psychopharmacology from Nottingham University. I have worked at the University of Sussex and spent the last nine years in the Department of Psychiatry here in Oxford. During my postdoctoral career, I have gained broad range of experience investigating brain function in both patient populations and healthy volunteers, using MRI and MEG. I managed a number of experimental medicine studies, phase 3 clinical trials and a device trial in collaboration with industrial partners. I am also a trained secondary science teacher and was Head of Biology before returning to research in 2013. I am passionate about public engagement and I am an In2Science mentor to encourage students into STEM.
Catechol-O-methyltransferase activity does not influence emotional processing in men.
Martens MA. et al, (2022), J Psychopharmacol
Deep brain stimulation of the nucleus accumbens in severe enduring anorexia nervosa: a pilot study
SCAIFE J. et al, (2022), Frontiers in Behavioral Neuroscience
A Longitudinal Magnetoencephalographic Study of the Effects of Deep Brain Stimulation on Neuronal Dynamics in Severe Anorexia Nervosa.
Braeutigam S. et al, (2022), Front Behav Neurosci, 16
Translating the promise of 5HT4 receptor agonists for the treatment of depression.
Murphy SE. et al, (2021), Psychol Med, 51, 1111 - 1120
Study protocol: Using deep brain stimulation, multimodal neuroimaging and neuroethics to understand and treat severe enduring Anorexia Nervosa.
Park RJ. et al, (2018), Frontiers in Psychiatry