BSc (Hons) PhD PGCE
Operational Lead NDS SITU
- Clinical Trial Manager (PART Trial)
I am the Clinical Trial Manager for the PART Trial (Partial prostate Ablation versus Radical prosTatectomy). This is Phase III RCT with long-term follow-up. 800 men to be recruited over five years in at least 10 NHS Urology departments. Participant will be randomised to either Radical treatment (RP, RRT or LDR-B) or Partial ablation using IRE (Irreversible Electroporation) or HIFU (high Intensity Focused Ultrasound). I work in SITU (Surgical Interventions Trial Unit) and Freddie Hamdy and Richard Bryant are co-CI with Tom Leslie local PI.
I have been in research for over two decades. I hold an honours degree in neuroscience and a PhD in psychopharmacology from Nottingham University. I have worked at the University of Sussex and spent the last nine years in the Department of Psychiatry here in Oxford. During my postdoctoral career I have gained broad range of experience investigating brain function in both patient populations and healthy volunteers, using MRI and MEG. I managed a number of experimental medicine studies, phase 3 clinical trials and a device trial in collaboration with industrial partners. I am also a trained secondary science teacher and was Head of Biology before returning to research in 2013. I am passionate about public engagement and I am an In2Science mentor to encourage students into STEM.
Catechol-O-methyltransferase activity does not influence emotional processing in men.
Martens MA. et al, (2022), J Psychopharmacol
Deep brain stimulation of the nucleus accumbens in severe enduring anorexia nervosa: a pilot study
SCAIFE J. et al, (2022), Frontiers in Behavioral Neuroscience
Translating the promise of 5HT4 receptor agonists for the treatment of depression.
Murphy SE. et al, (2021), Psychol Med, 51, 1111 - 1120
Study protocol: Using deep brain stimulation, multimodal neuroimaging and neuroethics to understand and treat severe enduring Anorexia Nervosa.
Park RJ. et al, (2018), Frontiers in Psychiatry
Study Protocol: Using Deep-Brain Stimulation, Multimodal Neuroimaging and Neuroethics to Understand and Treat Severe Enduring Anorexia Nervosa.
Park RJ. et al, (2018), Front Psychiatry, 9