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LOCATION

Botnar Research Centre, Old Road, Headington, Oxford OX3 7LD

Alice Guazzelli

PhD


Clinical Trial Manager

My role is Clinical Trial Manager within the Surgical Intervention Trials Unit (SITU), where she works on two clinical trials: SARONG and ART.

SARONG is a randomised controlled trial of intensive surveillance versus standard postoperative follow-up in patients who have undergone surgery for oesophageal and gastric cancer. Funded by the NIHR, the study began recruiting in June 2023 and successfully closed recruitment on 31 March 2026, with 974 participants enrolled. The trial is now in the follow-up phase, which is expected to continue until 31 March 2029.

ART is an international multi-centre randomised trial comparing bilateral internal mammary grafting with single internal mammary grafting in coronary revascularisation. The 15-year follow-up study, funded by the British Heart Foundation and investigating long-term survival and clinical outcomes following coronary artery bypass grafting, has now been completed, with results currently being prepared for publication.

In addition, I have been leading the NDS Outreach Framework project since its launch in August 2024.

Previously, I worked as a Research Fellow within the Colorectal Cancer Genetics Group at the Institute of Genetics and Cancer, University of Edinburgh. The main focus of my project was working on chemoprevention targeting colonic stem cell population in colorectal cancer models. Prior to that, I was awarded a PhD in Biological Sciences from the University of Salford, where my project at the Biomedical Research Centre involved working on new therapeutic targets for malignant mesothelioma.