Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

A new online training tool being developed by the Genomics Education Programme for scientists processing tumour samples for whole genome sequencing will feature Dr Clare Verrill, a Senior Clinical Lecturer in Pathology at the Nuffield Department of Surgical Sciences.

Many of the first healthcare professionals to use the tool will be those processing tumour samples for Genomics England’s 100,000 Genomes Project, which aims to analyse whole genome sequences from thousands of patients to develop a greater understanding of the basis of disease. The insights gained from the project will have a huge impact on histopathology.

Whole genome sequencing can only be successfully performed on DNA from tumour samples with a suitable percentage of tumour tissue and the minimum required amount of DNA. This new training tool will consist of four educational modules and one assessment module covering tumour assessment for whole genome sequencing and introducing one reliable method of assessing tumour samples in 3D. It is anticipated that histopathologists, clinical and biomedical scientists working in NHS Genomic Medicine Centres will be the first to use the tool.  

Dr Verrill, who is the Lead for Molecular Pathology at the Oxford Genomic Medicine Centre, provides an introduction to the modules and the assessment model, explaining why there is a need for standardised training. Dr Verrill said: ‘Ultimately, the goal of this training tool is to help us deliver a better service to patients. If we can assess a tumour for genomic sequencing accurately and efficiently, we will ensure that as many eligible samples as possible are selected for DNA extraction and sequencing with minimal delay or errors.

‘And of course, the goal beyond that is that, in time, we will gain a much deeper understanding of cancer at a molecular level, to better inform our patients’ diagnosis, treatment and prognostic information.’

The tool will be launched by the Genomics Education Programme in spring 2017.

Read more about the 100,000 Genomes Project.

Similar stories

Oxford's largest ever study into varicose veins shows need for surgery is linked to genetics

Varicose veins are a very common manifestation of chronic venous disease, affecting over 30% of the population in Western countries. In America, chronic venous disease affects over 11 million men and 22 million women aged 40–80 years old. Left untreated it can escalate to multiple health complications including leg ulcers and ultimately amputations. A new international study by Oxford researchers published on 2 June 2022 in Nature Communications establishes for the first time, a critical genetic risk score to predict the likelihood of patients suffering with varicose veins to require surgery, as well as pointing the way towards potential new therapies.

New reporting guidelines developed to improve AI in healthcare settings

New reporting guidelines, jointly published in Nature Medicine and the BMJ by Oxford researchers, will ensure that early studies on using Artificial Intelligence (AI) to treat real patients will give researchers the information needed to develop AI systems safely and effectively.

Results of the REF 2021: congratulations and thank you

Today, the UK funding bodies have published the results of the UK’s most recent national research assessment exercise, the Research Excellence Framework (REF) 2021.

Blog posts

Oxford MedSci goes silver: 10 Years of Athena SWAN

The Medical Sciences Division is celebrating 10 years since its first Athena Swan bronze application, and the first year in which all 16 of its departments have achieved a silver award. The silver award recognises commitment to gender equality, understanding culture and context, and more. Read about our department’s hard work and innovation.

Lights, camera, action! My journey into video production

Dr Hannah McGivern provides a 'behind-the-scenes' account of her experience producing the video 'Journey of a QUOD Sample: Donating to Transplant Research', supported by the funds from the University of Oxford Public Engagement with Research (PER) Seed Fund.

Mentoring in practice

NDS has launched a new, interdepartmental mentoring scheme called RECOGNISE. In this podcast, Gemma Horbatowski (HR Advisor) interviews Monica Dolton (Programme Manager and Research Project Manager) about her experiences of mentor-mentee relationships.