Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Dr Clare Verrill and Dr Lisa Browning have been filmed demonstrating how to sample fresh tumours from prostate and renal cases for whole genome sequencing and the 100,000 Genomes Project.

Dr Clare Verrill demonstrating how to biobank prostate specimens

In interviews, Dr Verrill, who is a Senior Clinical Lecturer in Pathology at the Nuffield Department of Surgical Sciences and an Honorary Consultant in Cellular Pathology at Oxford University Hospitals NHS Foundation Trust, and Dr Browning (pictured below), who is an Honorary Senior Clinical Lecturer in Pathology at Oxford University and a Consultant Histopathologist, also discussed the benefits of sampling fresh tissue compared to formalin fixed samples.

Dr Lisa Browning demonstrating how to sample fresh tumours from renal cases.© NDSThe 100,000 Genomes Project aims to analyse whole genome sequences from thousands of patients to develop a greater understanding of the basis of disease. Around 1,200 samples from about 600 cancer patients and around 2,000 samples from about 660 rare disease patients will be collected.

It is vital that every patient who enrols on the cancer programme receives an accurate and timely report of the results of their whole genome sequencing. Every sample collected must deliver optimum insight and this will require changes to the way samples are handled.

Advances in genetic analysis and cheaper whole genome sequencing means sampling fresh tissue is now set to be standard cancer care. 

The videos will be hosted on the Genomics England website and disseminated across the NHS to support pathologists and other members of cancer multi-disciplinary teams with recruitment of patients on to the 100,000 Genomes Project and other similar genomics studies. They will also be shared with Health Education England and the Royal College of Pathologists for education and training.   

View all the videos featuring Dr Clare Verrill and Dr Lisa Browning here.

Similar stories

Catherine Lovegrove wins Best Poster Prize at BAUS Endourology Meeting

Congratulations to Miss Catherine Lovegrove from the Nuffield Department of Surgical Sciences on winning the Best Poster Prize at the 2022 British Association of Urological Surgeons (BAUS) Endourology Section Annual Meeting.

Two Oxford surgeons elected in the 2022 RCSEd Council and Trainee Elections

Congratulations to Miss Katie Hurst and Mr Michael Silva who were elected in the Royal College of Surgeons of Edinburgh (RCSEd) 2022 Council and Trainee Elections.

Genetic mapping of tumours reveals how cancers grow

Researchers from the University of Oxford, KTH Royal Institute of Technology, Science for Life Laboratory, and the Karolinska Institutet, Solna, Sweden, have found that individual prostate tumours contain a previously unknown range of genetic variation.

Blog posts

Oxford MedSci goes silver: 10 Years of Athena SWAN

The Medical Sciences Division is celebrating 10 years since its first Athena Swan bronze application, and the first year in which all 16 of its departments have achieved a silver award. The silver award recognises commitment to gender equality, understanding culture and context, and more. Read about our department’s hard work and innovation.

Lights, camera, action! My journey into video production

Dr Hannah McGivern provides a 'behind-the-scenes' account of her experience producing the video 'Journey of a QUOD Sample: Donating to Transplant Research', supported by the funds from the University of Oxford Public Engagement with Research (PER) Seed Fund.

Mentoring in practice

NDS has launched a new, interdepartmental mentoring scheme called RECOGNISE. In this podcast, Gemma Horbatowski (HR Advisor) interviews Monica Dolton (Programme Manager and Research Project Manager) about her experiences of mentor-mentee relationships.