Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Total energy expenditure (TEE) was measured over two 10-day periods, before and after operation in 16 patients undergoing coronary artery surgery and randomized to have cardiopulmonary bypass with an intraoperative blood temperature of either 28 or 20 degrees C. TEE was measured with doubly labelled water containing stable isotopes of hydrogen and oxygen to allow calculation of TEE over fixed periods from the differential rate of excretion of the two isotopes. Results were available for eight patients in the 28 degrees C group but for only seven in the 20 degrees C group (one patient in this group was excluded as the temperature allocated was not achieved). The groups were similar with respect to body-weight and lean body mass. The 20 degrees C group received more grafts than the 28 degrees C group, resulting in an increase in cross-clamp and bypass times. Mean preoperative TEE was similar in both groups. The mean difference in fractional turnover rates of hydrogen and oxygen was not significantly different in the postoperative period. There was a non-significant increase in the mean 10-day postoperative TEE, calculated in total calories, of 4.7 per cent in the 28 degrees C and 5.1 per cent in the 20 degrees C group. When changes in postoperative TEE were calculated according to lean body mass, the mean increases were respectively 3.7 and 3.2 per cent. Cardiac surgery utilizing cardiopulmonary bypass and intraoperative hypothermia results in only a modest increase in postoperative TEE. In this study a more profound level of intraoperative hypothermia did not influence the change in postoperative TEE.

Original publication

DOI

10.1002/bjs.1800780236

Type

Journal article

Journal

Br J Surg

Publication Date

02/1991

Volume

78

Pages

237 - 241

Keywords

Adult, Body Mass Index, Body Water, Cardiopulmonary Bypass, Coronary Artery Bypass, Deuterium, Energy Metabolism, Humans, Hypothermia, Induced, Male, Methods, Middle Aged, Oxygen Isotopes, Prospective Studies, Random Allocation