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The traditional approach to surgical resection of colonic cancer involves removal of the primary tumor together with the associated lymphovascular pedicle. In an attempt to improve oncological outcomes, several groups have recently published data describing improved outcomes with a more radical surgical approach termed complete mesocolic excision (CME) with central vessel ligation (CVL). Here we critically appraise this new surgical advance and discuss other surgical options suggested to offer improvements over current best practice.

Original publication




Journal article


Surg Oncol Clin N Am

Publication Date





25 - 34


Colon cancer, Complete mesocolic excision, Lymph node, Surgery, Colectomy, Colonic Neoplasms, Humans, Practice Guidelines as Topic