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Clopidogrel is a potent inhibitor of platelet aggregation and has been used as an alternative, or as an adjunct to aspirin in reducing the risk of thrombosis. A 34-year-old uremic type 1 male diabetic patient who underwent simultaneous kidney-pancreas transplantation was given clopidogrel as he was allergic to aspirin. He developed polyarthralgia one week later, followed in a few days by symmetrical migratory polyarthritis, which resolved completely on withdrawing the drug. The implications to clinical management in a transplant setting are discussed.

Original publication




Journal article


Int J Immunopathol Pharmacol

Publication Date





443 - 444


Adult, Arthritis, Diabetes Mellitus, Type 1, Humans, Kidney Function Tests, Kidney Transplantation, Male, Pancreas Transplantation, Platelet Aggregation Inhibitors, Postoperative Complications, Ticlopidine, Uremia