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Thrombosis of the transplanted pancreas is a common and often catastrophic event. Predisposing factors include the hypercoagulable state of many patients with diabetic renal failure, preservation-related graft endothelial injury, and low-velocity venous flow. Clinical management includes optimization of modifiable risk factors, controlled anticoagulation, graft monitoring, and early therapeutic intervention.

Original publication

DOI

10.1097/TP.0b013e3181eb2ea0

Type

Journal article

Journal

Transplantation

Publication Date

15/10/2010

Volume

90

Pages

705 - 707

Keywords

Anticoagulants, Blood Flow Velocity, Diabetic Nephropathies, Endothelium, Humans, Pancreas Transplantation, Pancreatectomy, Splenic Vein, Thrombosis, Transplantation, Homologous