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Gene therapy holds a great promise to prevent allograft rejection or to induce transplant tolerance. Many achievements in vector development have allowed the progression of this therapy to become more attainable in clinical transplantation. In this articles, the authors examine the exciting development in various vector technologies that allows this form of therapy to take the central stage of clinical transplantation. Also highlighted are various therapeutic strategies that might ultimately result in the realization of gene-based treatment in clinical transplantation.

Type

Journal article

Journal

Discov Med

Publication Date

08/2006

Volume

6

Pages

153 - 156

Keywords

Animals, Genetic Therapy, Genetic Vectors, Humans, Transplantation, Homologous, Viruses