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OBJECTIVES: Comparison of the accuracy of prediction of contemporary mortality prediction models after open Abdominal Aortic Aneurysm (AAA) surgery. METHODS: Post-operative data were collected from AAA patients from 2 UK Intensive Care Units (ICU). POSSUM and VBHOM based models were compared to the APACHE-AAA model which was able to adjust for the hospital-related effect on outcome. Model performance was assessed using measures of calibration, discrimination and subgroup analysis. RESULTS: 541 patients were studied. The in-hospital mortality rate for elective AAA repair (325 patients) was: 6.2% (95% confidence interval (c.i.) 3.5 to 8.8) and for emergency repair (216 patients) was: 28.7% (95% c.i. 22.5-34.9). The APACHE-based model had the best overall fit to the whole population of AAA patients, and also separately in elective and emergency patients. The V-POSSUM physiology-only (p<0.001) and VBHOM (p=0.011) models had a poor fit in elective patients. The RAAA-POSSUM physiology-only (p<0.001) and VBHOM models (p=0.010) had a poor fit in emergency patients. CONCLUSIONS: The APACHE-AAA model with its ability to adjust for both the hospital-related "effect" as well as the patient case-mix, was a more accurate risk stratification model than other contemporary models, in the post-operative AAA patient managed in ICU.

Original publication

DOI

10.1016/j.ejvs.2006.11.016

Type

Journal article

Journal

Eur J Vasc Endovasc Surg

Publication Date

05/2007

Volume

33

Pages

536 - 543

Keywords

APACHE, Aged, Aortic Aneurysm, Abdominal, Female, Hospital Mortality, Humans, Male, Middle Aged, Models, Statistical, Prognosis, Risk Assessment, Severity of Illness Index, Survival Analysis, Vascular Surgical Procedures