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Triggered by the urgent need for greater accuracy in predicting the biological behaviour of diseases, foremost cancer, the search for the ideal biomarker—a molecule, gene or any other characteristic that can be objectively measured and evaluated—is relentless. The search for exemplary candidates has been encouraged by the rapid progress in profiling and detection technologies which have enhanced throughput and accuracy of protein, transcript and mutation detection. These advances are reflected in the sheer number of publications reporting discoveries and clinical evaluation of new genes or proteins of biomarker potential. (Figure Presented)

Original publication





Book title

Biomarkers of the Tumor Microenvironment, Second Edition

Publication Date



467 - 482