A simple method for measuring patient anti-globulin responses against isotypic or idiotypic determinants.
Cobbold SP., Rebello PR., Davies HF., Friend PJ., Clark MR.
A simple inhibition of capture enzyme-linked immunosorbent assay (IOC-ELISA) was developed which permitted the independent measurement of anti-idiotypic and anti-isotypic antiglobulins in serum samples from patients receiving therapeutic monoclonal antibodies.