Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Drugs can cause adverse effects on the urinary tract by a local action, or as a result of systemic effects on the autonomic nervous system, or central nervous control of bladder emptying. Tiaprofenic acid and cyclophosphamide as its metabolite acrolein, for example, can cause haemorrhagic cystitis. Localised retroperitoneal fibrosis, from methysergide, for instance, can lead to hydronephrosis. Agents with anticholinergic actions, such as the tricyclic antidepressants, can result in urinary retention, whilst alpha-adrenoceptor antagonists may lead to stress incontinence in females.

Type

Journal article

Journal

Adverse Drug Reaction Bulletin

Publication Date

01/12/1998

Pages

735 - 738