Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

With increasing demand for donor organs for transplantation, machine perfusion (MP) promises to be a beneficial alternative preservation method for donor livers, particularly those considered to be of suboptimal quality, also known as extended criteria donor livers. Over the last decade, numerous studies researching MP of donor livers have been published and incredible advances have been made in both experimental and clinical research in this area. With numerous research groups working on MP, various techniques are being explored, often applying different nomenclature. The objective of this review is to catalog the differences observed in the nomenclature used in the current literature to denote various MP techniques and the manner in which methodology is reported. From this analysis, we propose a standardization of nomenclature on liver MP to maximize consistency and to enable reliable comparison and meta-analyses of studies. In addition, we propose a standardized set of guidelines for reporting the methodology of future studies on liver MP that will facilitate comparison as well as clinical implementation of liver MP procedures.

Original publication

DOI

10.1111/ajt.13843

Type

Journal article

Journal

Am J Transplant

Publication Date

10/2016

Volume

16

Pages

2932 - 2942

Keywords

clinical research/practice, donors and donation: extended criteria, guidelines, liver transplantation/hepatology, organ perfusion and preservation, Guidelines as Topic, Humans, Liver Transplantation, Meta-Analysis as Topic, Organ Preservation, Perfusion, Research Report, Terminology as Topic, Tissue Donors