Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Whole-organ pancreas transplantation, either alone or combined with a kidney transplant, is the only definitive treatment for many patients with type 1 diabetes that restores normal glucose homoeostasis and insulin independence. Pancreas transplantation delays, or potentially prevents, secondary diabetes complications and is associated with improvement in patient survival when compared with either patients remaining on the waiting list or those receiving kidney transplant alone. Pancreas transplantation is safe and effective, with 1-year patient survival >97 % and graft survival rates of 85 % at 1 year and 76 % at 5 years in recent UK data. This review focuses on some current areas of interest in pancreas transplantation.

Original publication

DOI

10.1007/s00592-016-0865-x

Type

Journal article

Journal

Acta Diabetol

Publication Date

12/2016

Volume

53

Pages

871 - 878

Keywords

Diabetes, Incretin, Pancreas transplant, Diabetes Complications, Diabetes Mellitus, Type 1, Humans, Incretins, Insulin, Kidney Transplantation, Pancreas Transplantation, Survival Rate, Time-to-Treatment, Treatment Outcome