Developing new age-specific prostate-specific antigen thresholds for testing for prostate cancer.
Gilbert R., Tilling K., Martin RM., Lane JA., Davis M., Hamdy FC., Neal DE., Donovan JL., Metcalfe C.
PURPOSE: To examine whether age-related reference ranges for "normal" prostate-specific antigen (PSA) change (determined in men without prostate cancer) can be used to identify men at high risk of having prostate cancer. METHODS: Subjects were men aged 50-69 years with PSA