Measurement of a 5-gene panel in whole blood in kidney transplant recipients with acute rejection and stable controls
Betts G., Van Der Net J., Shankar S., Friend P., Harden P., Wood K.
New biomarkers are required to detect acute rejection (AR) in kidney transplant recipients (KTRs) to avoid invasive kidney biopsies. We assess whether a 5-gene panel (DUSP1; NKTR; PBEF1; MAPK9; and PSEN1) in whole blood samples that has previously been shown to identify AR in a paedriatric KTR population is able to distinguish AR in a UK population of adult Caucasian KTR patients.