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Coronary revascularization for coronary artery disease dates back to the introduction of coronary bypass by Favaloro in 1967 and coronary angioplasty by Gruentzig in 1977 (first published in 1968 and 1978, respectively). There have been many technical improvements over the ensuing 5 decades, studied in clinical trials. This article reviews the history of coronary revascularization (the development of optimal medical therapy) and points the way to the future of stable coronary artery disease management.

Original publication




Journal article


Am J Med

Publication Date





1285 - 1292


Coronary artery bypass surgery, Optimal medical therapy, Percutaneous coronary intervention, Randomized clinical trials, Revascularization, Coronary Artery Bypass, Coronary Artery Disease, History, 20th Century, History, 21st Century, Humans