Adipocyte autophagy limits gut inflammation by controlling oxylipin and IL-10.
Journal article
Richter FC. et al, (2023), EMBO J
Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease.
Journal article
Leng H. et al, (2022), Nat Commun, 13
Multiple myeloma metabolism – a treasure trove of therapeutic targets?
Journal article
Roman-Trufero M. et al, (2022), Frontiers in Immunology, 13
Editorial - Cancer and Bone special issue.
Journal article
Edwards CM. and Drake MT., (2022), Bone, 158
Metabolic profiling of prostate cancer in skeletal microenvironments identifies G6PD as a key mediator of growth and survival.
Journal article
Whitburn J. et al, (2022), Sci Adv, 8
The antidiabetic drug metformin acts on the bone microenvironment to promote myeloma cell adhesion to preosteoblasts and increase myeloma tumour burden in vivo
Journal article
Gámez B. et al, (2022), Translational Oncology, 15, 101301 - 101301
Cell-extrinsic autophagy in mature adipocytes regulates anti-inflammatory response to intestinal tissue injury through lipid mobilization
Preprint
Richter FC. et al, (2021)
Management of bone metastasis and cancer treatment-induced bone loss during the COVID-19 pandemic: An international perspective and recommendations.
Journal article
Brown JE. et al, (2021), J Bone Oncol, 29
Myeloma and marrow adiposity: Unanswered questions and future directions.
Journal article
Morris EV. and Edwards CM., (2021), Best Pract Res Clin Endocrinol Metab, 35
Advances in the molecular pharmacology of bone and cancer-related bone diseases.
Journal article
Edwards CM. and Russell RGG., (2021), Br J Pharmacol, 178, 1889 - 1890
Morphogens and growth factor signalling in the myeloma bone-lining niche.
Journal article
Morris EV. and Edwards CM., (2021), Cell Mol Life Sci
Biological relationship between bone and myeloma cells
Chapter
Edwards CM. and Lawson MA., (2021), Bone Cancer: Bone Sarcomas and Bone Metastases - From Bench to Bedside, 1005 - 1017
Modeling the Human Bone-Tumor Niche: Reducing and Replacing the Need for Animal Data.
Journal article
Rao SR. et al, (2020), JBMR Plus, 4
Myeloma cells down-regulate adiponectin in bone marrow adipocytes via TNF-alpha.
Journal article
Morris EV. et al, (2019), J Bone Miner Res
Cholesterol promotes myeloma cell viability and increases bone marrow myeloma tumour burden in vivo
Conference paper
Beatriz G. et al, (2019), JOURNAL OF BONE AND MINERAL RESEARCH, 34, 198 - 198
Cholesterol promotes myeloma cell viability and increases bone marrow myeloma tumour burden in vivo
Conference paper
Beatriz G. et al, (2019), JOURNAL OF BONE AND MINERAL RESEARCH, 34, 198 - 198
Pretreatment with the antidiabetic drug metformin alters the bone microenvironment to increase myeloma tumour burden and bone disease in vivo
Conference paper
Gamez B. et al, (2019), JOURNAL OF BONE AND MINERAL RESEARCH, 34, 197 - 197
Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease.
Journal article
Gooding S. et al, (2019), Nat Commun, 10
Multiple myeloma increases nerve growth factor and other pain-related markers through interactions with the bone microenvironment.
Journal article
Olechnowicz SWZ. et al, (2019), Sci Rep, 9
Small Animal Video Tracking for Activity and Path Analysis Using a Novel Open-Source Multi-Platform Application (AnimApp).
Journal article
Rao SR. et al, (2019), Sci Rep, 9