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Tumour heterogeneity and evolutionary dynamics in colorectal cancer

Journal article

Chan DKH. and Buczacki SJA., (2021), Oncogenesis, 10

Targeting acid ceramidase to improve the radiosensitivity of rectal cancer

Journal article

Clifford R. et al, (2020), Cells

5-hydroxymethylcytosine and gene activity in mouse intestinal differentiation

Journal article

Uribe-Lewis S. et al, (2020), Scientific Reports, 10

Fate plasticity in the intestine: The devil is in the detail.

Journal article

Buczacki S., (2019), World J Gastroenterol, 25, 3116 - 3122

Itraconazole targets cell cycle heterogeneity in colorectal cancer.

Journal article

Buczacki SJA. et al, (2018), J Exp Med, 215, 1891 - 1912

Itraconazole perturbs colorectal cancer dormancy through SUFU-mediated WNT inhibition.

Journal article

Popova SA. and Buczacki SJA., (2018), Mol Cell Oncol, 5

Mex3a Marks a Slowly Dividing Subpopulation of Lgr5+ Intestinal Stem Cells.

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Barriga FM. et al, (2017), Cell Stem Cell, 20, 801 - 816.e7

Adenomas as a risk factor in familial colorectal cancer: implications for screening and surveillance in the UK.

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Buczacki SJA. and Wheeler JMD., (2016), Colorectal Dis, 18, 842 - 845

Isolation of Human Colon Stem Cells Using Surface Expression of PTK7.

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Jung P. et al, (2015), Stem Cell Reports, 5, 979 - 987

Mouse models of colorectal cancer as preclinical models.

Journal article

McIntyre RE. et al, (2015), Bioessays, 37, 909 - 920

The confounding effects of tumour heterogeneity and cellular plasticity on personalized surgical management of colorectal cancer.

Journal article

Buczacki SJA. and Davies RJ., (2014), Colorectal Dis, 16, 329 - 331

Side population sorting separates subfractions of cycling and non-cycling intestinal stem cells.

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von Furstenberg RJ. et al, (2014), Stem Cell Res, 12, 364 - 375

Colon resection: is standard technique adequate?

Journal article

Buczacki SJA. and Davies RJ., (2014), Surg Oncol Clin N Am, 23, 25 - 34

Defining stem cell dynamics in models of intestinal tumor initiation.

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Vermeulen L. et al, (2013), Science, 342, 995 - 998

Intestinal label-retaining cells are secretory precursors expressing Lgr5.

Journal article

Buczacki SJA. et al, (2013), Nature, 495, 65 - 69

Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling.

Journal article

Wong VWY. et al, (2012), Nat Cell Biol, 14, 401 - 408

Stem cells, quiescence and rectal carcinoma: an unexplored relationship and potential therapeutic target.

Journal article

Buczacki S. et al, (2011), Br J Cancer, 105, 1253 - 1259

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