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Publications

GeneFEAST: the pivotal, gene-centric step in functional enrichment analysis interpretation

TAYLOR A., (2023)

A Phase Ib/II study of IGF-neutralising antibody xentuzumab with enzalutamide in metastatic castration-resistant prostate cancer.

Macaulay VM. et al, (2023), Br J Cancer

WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma.

Coupe N. et al, (2023), Cell Oncol (Dordr), 46, 391 - 407

CHK1 inhibition exacerbates replication stress induced by IGF blockade

Macaulay V. et al, (2021), Oncogene

IGF-1R nuclear import and recruitment to chromatin involves both alpha and beta subunits.

Mills JV. et al, (2021), Discov Oncol, 12

IGF-1R nuclear import and recruitment to chromatin involves both alpha and beta subunits

Mills JV. et al, (2021), Discover Oncology

Targeting IGF Perturbs Global Replication through Ribonucleotide Reductase Dysfunction.

Rieunier G. et al, (2021), Cancer Res, 81, 2128 - 2141

IGF targeting perturbs global replication through ribonucleotide reductase dysfunction.

RIEUNIER G. et al, (2020), BioRxiv

CHK1 inhibition exacerbates replication stress induced by IGF blockade.

WU X. et al, (2020), TBC

Type 1 IGF receptor associates with adverse outcome and cellular radioresistance in paediatric high-grade glioma.

Simpson AD. et al, (2020), Br J Cancer, 122, 624 - 629

Dual-specificity protein phosphatase DUSP4 regulates response to MEK inhibition in BRAF wild-type melanoma.

Gupta A. et al, (2020), Br J Cancer, 122, 506 - 516

Radioresistant laryngeal cancers upregulate type 1 IGF receptor and exhibit increased cellular dependence on IGF and EGF signalling.

Qureishi A. et al, (2019), Clin Otolaryngol, 44, 1026 - 1036

Therapeutic Targeting of the IGF Axis.

Osher E. and Macaulay VM., (2019), Cells, 8

Increased EZH2 expression in prostate cancer is associated with metastatic recurrence following external beam radiotherapy.

Wu X. et al, (2019), Prostate, 79, 1079 - 1089

Bad to the Bone: The Role of the Insulin-Like Growth Factor Axis in Osseous Metastasis.

Rieunier G. et al, (2019), Clin Cancer Res, 25, 3479 - 3485

Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage.

Aleksic T. et al, (2018), Cancer Res, 78, 3497 - 3509

Insulin Like Growth Factor Receptor 1 (IGF-1R) and Radiotherapy Resistance in Laryngeal Squamous Cell Cancer (LSCC)

Qureishi None. et al, (2018)

RAPTOR up-regulation contributes to resistance of renal cancer cells to PI3K-mTOR inhibition.

Earwaker P. et al, (2018), PLoS One, 13

IGF-1R associates with adverse outcomes after radical radiotherapy for prostate cancer.

Aleksic T. et al, (2017), Br J Cancer, 117, 1600 - 1606

Insulin-Like Growth Factor (IGF) Pathway Targeting in Cancer: Role of the IGF Axis and Opportunities for Future Combination Studies.

Simpson A. et al, (2017), Target Oncol, 12, 571 - 597

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