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If you agree to participate in the study, you will be started on treatment with endocrine therapy immediately.

People may feel that breast cancer should be removed by surgery as soon as possible. However, we now know that this may not always be the best strategy, and surgery is one treatment amongst several others.

There are already known benefits to starting other treatments before surgery in particular circumstances. This may allow us to reduce the tumour size before surgery, assess the response to other treatments, and gives us more time to plan the surgery.