Professor of Vascular Surgery
I am a Principal Investigator in the Asymptomatic Carotid Surgery Trial (ACST-2), one of the world's largest clinical surgery trials, involving thousands of patients from 30 countries. Our group reported that prophylactic surgery removing tight carotid artery narrowing (carotid endarterectomy) prevents future fatal and disabling strokes for at least 10 years. This finding has changed worldwide surgical and stroke practice (Lancet 2004, 2010).
National Audit: Our group instigated and reported the UK Carotid Surgery Audit (2005-8), the largest National Audit of carotid surgery in the UK. This work highlighted shortcomings in the NHS process of referral and of carrying out prompt carotid artery surgery; we work with the National Stroke Strategy providing a driver for preventing stroke by improving surgical services (British Medical Journal, 2009).
Collaborative research; government-funded (NIHR): I work with the University of Oxford Clinical Trial Service Unit (CTSU) evaluating two stroke prevention technologies in ACST-2, a large international trial comparing Carotid Endarterectomy with Carotid Artery Stenting. This work enables surgeons, stroke physicians, neurologists, cardiologists and interventional radiologists from many countries to work together.
2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk
HALLIDAY A. et al, (2019), For Presentation at the European Society of Cardiology on 2nd September 2019
Response to Comment on "High Operator and Hospital Volume are Associated With a Decreased Risk of Death and Stroke Following Carotid Revascularization: A Systematic Review and Meta-analysis: Authors' Reply".
Poorthuis MHF. et al, (2019), Ann Surg, 270, e50 - e51
High Operator and Hospital Volume Are Associated With a Decreased Risk of Death and Stroke After Carotid Revascularization: A Systematic Review and Meta-analysis.
Poorthuis MHF. et al, (2019), Ann Surg, 269, 631 - 641
Long-term outcomes of stenting and endarterectomy for symptomatic carotid stenosis: a preplanned pooled analysis of individual patient data.
Brott TG. et al, (2019), Lancet Neurol, 18, 348 - 356
Safety of Carotid Revascularization in Patients With a History of Coronary Heart Disease.
Volkers EJ. et al, (2019), Stroke, 50, 413 - 418