John Radcliffe Hospital, Level 5 and 6, Headley Way, Headington, Oxford, OX3 9DU
I qualified in Medicine from University College London with an intercalated BSc in Immunology and Cell Pathology. I subsequently completed a MSc in Burns, Plastic and Reconstructive Surgery before undertaking a DPhil in the Transplantation Research and Immunology Group (TRIG) at the University of Oxford. During my DPhil I developed an advanced preclinical model of human skin transplant rejection and a novel anti-rejection therapy. I am currently completing an academic clinical fellowship and specialty training in plastic surgery.
I am a consulting editor on the board of the journal Plastic & Reconstructive Surgery Global Open (PRS GO), produce the PRS GO Deep Cuts podcast ‘Giants in Plastic Surgery’ and serve on the Young Members Committee of the International Society of Liquid Biopsy. I am a tutor in Medicine at New College
If you are interested in collaborating or pursuing a research project, please get in touch!
BSc (Hons) MBBS MSc MRCS (Eng) DPhil
Academic Clinical Fellow in Plastic Surgery
My research focuses on understanding mechanisms of immune system activation and tolerance to inform the development of diagnostics and therapies that can improve outcomes for patients with cancer and patients with transplanted organs.
The immune system plays a crucial role in the body's defence against infection and cancer, however under- or overactivity can contribute to the development and progression of disease. Cancers are able to hijack the immune system by exploiting its normal mechanisms for identifying and destroying foreign invaders. Using a combination of advanced molecular techniques, I am currently investigating the development of immune system failure in the lymphatic system of patients with melanoma skin cancer. By doing so, I aim to identify biomarkers that can improve early prediction of metastatic risk and immunotherapy resistance.
At the other end of immune system dysfunction, transplant rejection occurs when the immune system recognises a transplanted organ as foreign and attempts to attack it. During my DPhil I explored overactive immune responses that can lead to skin transplant rejection and developed an advanced humanised pre-clinical model in which to simulate them. Building on this and our group’s work on regulatory T cell therapies, I aim to develop cellular therapies that can safely prevent the rejection of human skin allografts.
I am also passionate about interrogating inequity in science and medicine. By exploring its impact on our wider societies, my research in this area aims to help uncover solutions that can close the health gap.