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LOCATION

Radiobiology Research Institute, Churchill Hospital, Headington, Oxford

DPHIL START DATE

25 April 2022

PROJECT TITLE

Targeting IGFs as risk factors for prostate cancer progression

Supervisors

Professor Valentine Macaulay and Professor Ian Mills 

Research groups

Jinseon (Selena) Kim

BA


DPhil student

My research focus is on the insulin-like growth factor (IGF) axis and its immunosuppressive effects in prostate cancer. Based on associations of high circulating IGF-1 with prostate cancer risk and prostate cancer IGF-1R expression, I’m interested in understanding the anti-tumour effects of IGF blockade in prostate in vitro and in vivo, and through clinical trial in men with newly-diagnosed prostate cancer. 

I graduated from Cornell University (USA) with a BA in Biological Sciences and a minor in Business Administration. I then worked as a research assistant in Dr Soberman’s Lab at Harvard Medical School/Massachusetts General Hospital for three years, researching the mechanism and function behind a novel protein highly expressed in recurrent paediatric myeloid leukaemia patients. Afterwards, I moved to the UK in 2019 where I worked as a research assistant in Val Macaulay’s lab, investigating the effect of IGF inhibition in prostate cancer progression.