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Dr Fadi Issa from Oxford University's Nuffield Department of Surgical Sciences has been selected as the winning recipient of a grant for a GeoMx™ Digital Spatial Profiler (DSP) from NanoString Technologies, a provider of life science tools for translational research and molecular diagnostic products.

Mrs Monica Dolton (NDS Project Manager), Dr Fadi Issa and Dr Joanna Hester (NDS Senior Postdoctoral Researcher)

The DSP instrument is part of the DSP Instrument Grant program, which included more than 100 submissions from around the world.

“Spatial genomics has the potential to make a major impact in transplantation research. Digital Spatial Profiling will allow us to collect comprehensive biological information from our precious tissue samples, including highly informative topographic data,” stated Dr Issa, who is Principal Investigator at the Transplantation Research Immunology Group (TRIG) in the Nuffield Department of Surgical Sciences. “We’re currently involved in a clinical trial of a novel cellular therapy, regulatory T cells in renal transplantation, and we believe DSP will be invaluable in understanding patient response and guiding future decisions in this important program.”

Chad Brown, senior vice president of sales and marketing of NanoString Technologies, said: “We are honoured to announce that Dr Fadi Issa from the University of Oxford has been selected as the winning recipient of a grant for our GeoMx™ Digital Spatial Profiler. The University of Oxford is home to an internationally recognized organ transplant program with a strong research focus on transplant immunology. NanoString is excited to engage the transplant community with our unique solution for spatial genomics.”

NanoString's GeoMx™ Digital Spatial Profiling Technology enables the precise quantification of 10’s to 1000’s of proteins and or RNA targets mapped to their location within a heterogeneous tissue. NanoString and its collaborators have presented GeoMx DSP data in more than a dozen abstracts at major scientific meetings, demonstrating the utility of DSP profiling to address a wide range of biological questions in Formalin Fixed Paraffin Embedded (FFPE) tissues.

The GeoMx™ Digital Spatial Profiler is currently in development and is expected to be commercially available in mid-2019. Today, Digital Spatial Profiling technology can be accessed through NanoString’s Technology Access Program (TAP). To date, over 40 customers have completed more than 55 TAP projects and processed over 1000 samples.  The results from these studies highlight the performance of DSP in at least ten abstracts presented at major scientific meetings and several publications in press.

Interested parties can learn more about DSP by visiting the NanoString Technologies website.  

Press release courtesy of NanoString Technologies.

 

 

Media coverage

NanoString Announces the University of Oxford Selected as the Winning Recipient in GeoMx Digital Spatial Profiler Grant Program
Nasdaq, 04/10/2018

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