John Radcliffe Hospital, Level 6, Headley Way, Headington, Oxford, OX3 9DU
Associate Professor of Plastic Surgery
- Wellcome Trust CRCD Fellow
- Consultant Plastic and Burns Surgeon
- Lecturer in Physiology
I jointly lead the Transplantation Research Immunology Group (TRIG) together with Dr Joanna Hester. TRIG is a dynamic group of graduate students, postdoctoral researchers and clinical academics with an interest in immune regulation. Our work spans basic science discoveries to early phase clinical trials of novel therapeutics. Our interests are focused on manipulating the immune system with a view to treating immune-mediated diseases such as transplant rejection and autoimmunity. We have a particular interest in the manipulation of regulatory T cells (Treg) and assessment of their functional characteristics. Our group currently runs the TWO Study, a phase IIb trial of Treg therapy in renal transplantation.
I chair the Transplantation Science Committee and the European Society for Organ Transplantation's Vascularised Composite Allograft Board. I am a Deputy Editor of the journal Transplantation and Associate Editor of the European Burns Journal. I am keen to promote basic and translational research and to support early career researchers. If you are interested in joining our group in the future please get in touch with me or Joanna Hester (firstname.lastname@example.org). Open positions are always advertised in the University's Gazette and online.
Prokopenko M. et al, (2022), European Burn Journal, 3, 362 - 369
Brook MO. et al, (2022), BMJ Open, 12
Moatti A. et al, (2022), J Immunother Cancer, 10
Fletcher CE. et al, (2022), Mol Cancer, 21
Beckett J. and Issa F., (2022), Transplantation, 106, 225 - 226