- Transplantation Research Immunology Group (TRIG) Research Group
NIHR Academic Clinical Lecturer
- Clinician Scientist
- Clinical Lecturer in Plastic Surgery
I am a researcher based in the Transplantation Research Immunology Group (TRIG) and the John Radcliffe Hospital respectively. I qualified in Medicine from the University of Oxford and completed my DPhil at the Nuffield Department of Surgery. My research interests are focused on manipulating the immune system with a view to improving outcomes after transplantation.Together with Dr Paul Harden and Professor Peter Friend, I am currently investigating regulatory T cell (Treg) therapy in renal transplantation in the Phase IIb TWO Study. I am also particularly interested in the immunometabolism of T lymphocytes as well as the mechanisms of rejection and regulation of vascularised composite allograft (VCA) and skin transplants. My work forms part of a number of successful collaborative studies with other members of TRIG, the NDS and the Oxford Transplant Centre.
Previously I have been funded by the Wellcome Trust, the Royal College of Surgeons Dunhill Medical Trust and the Oxford Health Services Research Committee, and I am currently the Duke of Kent Fellow at Restore and NIHR Clinical Lecturer. I am a member of the Basic Science Committee of the TTS and am keen to promote research to junior clinicians. I am also an enthusiastic teacher, and am Retained Lecturer in Anatomy at Exeter College.
The 2017 Transplantation Awards: Recognizing a Landmark Clinical Trial and a Basic Science Discovery With Far-Reaching Implications.
Grey ST. and Issa F., (2017), Transplantation, 101, 2655 - 2656
In View: Research Highlights.
Issa F., (2017), Transplantation, 101, 2649 - 2650
Selective blockade of CD28 on human T cells facilitates regulation of alloimmune responses.
Zaitsu M. et al, (2017), JCI Insight, 2
Issa F., (2017), Transplantation, 101, 1955 - 1956
Mesenchymal Stromal Cell Therapy: After the Gold Rush.
Issa F., (2017), Transplantation