NIHR Academic Clinical Lecturer
- Clinician Scientist
- Clinical Lecturer in Plastic Surgery
I am based in the Transplantation Research Immunology Group (TRIG) and the John Radcliffe Hospital. TRIG is a dynamic group of graduate students, postdoctoral researchers and junior clinical academics with an interest in immune regulation. I qualified in Medicine from the University of Oxford and completed my DPhil at the Nuffield Department of Surgical Science. My research interests are focused on manipulating the immune system with a view to improving outcomes after transplantation. Together with Dr Paul Harden and Professor Peter Friend, I am currently investigating regulatory T cell (Treg) therapy in renal transplantation in the MRC DPFS-funded Phase IIb TWO Study. I am particularly interested in the the effects of hypoxia on immune responses as well as the mechanisms of rejection and regulation of vascularised composite allograft (VCA) and skin transplants. My work forms part of a number of successful collaborative studies with other members of TRIG, the NDS and the Oxford Transplant Centre.
Previously I have been funded by the Wellcome Trust, the Royal College of Surgeons Dunhill Medical Trust and the Oxford Health Services Research Committee, and the Restore Research Trust I am Co-Chair of the Basic Science Committee of the TTS, and a member of the TTS Young Members Committee and the ESOT VCA Committee. I am an Associate Editor of the journal Transplantation. I am keen to promote basic and translationatl research to junior clinicians. I am also an enthusiastic teacher, and am Retained Lecturer in Physiology at Exeter College, Oxford.
If you are interested in joining our group in the future please get in touch with me or Joanna Hester (firstname.lastname@example.org). Open positions are advertised in the University's Gazette and online.
Regulatory T cells for tolerance.
Kawai K. et al, (2018), Hum Immunol, 79, 294 - 303
Preserving Treg Function: Beyond mTOR Inhibitors.
Adigbli G. and Issa F., (2018), Transplantation, 102, 179 - 182
Penile Allotransplantation for Penis Amputation after Ritual Circumcision: A Case Report with 24 Months of Follow-up
Issa F., (2018), Transplantation, 102, 1 - 2
Mesenchymal Stromal Cell Therapy: After the Gold Rush.
Issa F., (2018), Transplantation, 102, 7 - 8
The 2017 Transplantation Awards: Recognizing a Landmark Clinical Trial and a Basic Science Discovery With Far-Reaching Implications.
Grey ST. and Issa F., (2017), Transplantation, 101, 2655 - 2656