Contact information
LOCATION:
Institute of Developmental and Regenerative Medicine, Old Road Campus, Oxford OX3 7TY
John Radcliffe Hospital, Level 6, Headley Way, Headington, Oxford, OX3 9DU
Research groups
Colleges
Fadi Issa
DPhil FRCS(Plast)
Professor of Transplantation, Associate Head & Surgical Sciences Theme Lead
- Consultant Plastic, Reconstructive and Burns Surgeon
- Governing Body Fellow, Green Templeton College
- Academic Lead for Research Funding, Medical Sciences Division
I am Professor of Transplantation at the University of Oxford and a consultant surgeon. My work focuses on turning immunological insight into practical therapies that improve outcomes after organ and cell transplantation, and on broadening the use of immune targeted treatments in inflammatory and immune mediated disease. I integrate mechanistic immunology, biomarker and tissue based human studies, and early phase clinical trials, with a consistent emphasis on safety, durability, and real world implementation.
The Translational Research Immunology Group (TRIG) brings together graduate students, postdoctoral researchers, and clinical academics working across immunology, transplantation, tissue repair, and data driven translational science. We develop and test cellular and immunomodulatory therapies, and use deep immune profiling to understand mechanisms of response, resistance, and long term benefit. Our approach maintains a clear line of sight from discovery to patient impact.
Within Oxford, I serve as Associate Head of Department in the Nuffield Department of Surgical Sciences as Theme Lead for Surgical Sciences. I am also MSD Academic Lead for Research Funding and a Governing Body Fellow at Green Templeton College.
I am Editor in Chief of BMJ Immunology and an Executive Editor of Transplantation. I serve on the Steering Committee of FOCIS and previously chaired The Transplantation Society’s Transplantation Science Committee.
I am committed to building a rigorous and supportive training environment for early career researchers and clinicians, and welcome enquiries from prospective students, fellows, and collaborators.
Key publications
ssociation between deep cervical lymph node dissection and dementia incidence in patients with head and neck cancer: a systematic review
Journal article
Omar M. et al, (2026), European Journal of Plastic Surgery, 49
The functional resonance analysis method in healthcare: How knowledge is produced within and across scientific communities
Journal article
Lounsbury O. et al, (2026), Safety Science, 196
Editorial: Post pregnancy contraception
Journal article
Makins A., (2026), Best Practice and Research Clinical Obstetrics and Gynaecology, 105
Validating Primary and Secondary Healthcare Resource Use and Costs estimates in OMOP-Mapped vs Source CPRD-HES Data in the UK
Conference paper
Fabiano G. et al, (2026)
Causes of excess non-lymphoma death in 58,000 patients with DLBCL diagnosed during 1997-2020 and followed for up to 25 years.
Journal article
Challenger A. et al, (2026), Blood Adv
TCR T cells targeting IgA- and IgG-expressing multiple myeloma.
Journal article
Douvlataniotis K. et al, (2026), Blood
Reconsidering the 1 mm rule: Contextualising R1 margin status in rectal cancer.
Journal article
Mason JD. et al, (2026), Colorectal Dis, 28
Vortex-actuated pre-enrichment accelerates human regulatory T cell sorting and improves early fitness
Journal article
Ho QY. et al, (2026), Molecular Therapy Advances, 34, 201667 - 201667
Storage under hypoxia improves the ability of red cells to release oxygen in ex vivo–perfused human kidneys
Journal article
Rabcuka J. et al, (2026), Blood Red Cells & Iron, 2, 100038 - 100038
0594 Drug-testing in patient-derived renal cell carcinoma organoids reveals pathways of vulnerability and resistance
Journal article
Steven M. et al, (2026), European Urology, 89, S1 - S2
The PRAGMATIC pathway - PRostate cancer diAGnosis and MAnagement Triage In Clinical care.
Journal article
Sharma A. et al, (2026), BJU Int
Developing and validating a neonatal screening tool for congenital anomalies to be used in low- and middle-income country settings.
Journal article
Gebreselassie HA. and Lakhoo K., (2026), BMJ Glob Health, 11
Substantial international variation in the cost of blood group and save and crossmatch: A systematic review.
Journal article
Fabiano G. et al, (2026), Br J Haematol
Mast-cell derived nerve growth factor drives ILC2 pro-tumoral functions in bladder cancer.
Journal article
Falquet M. et al, (2026), Nat Commun
Comparative safety, efficacy, and predictors of complete occlusion of flow diverter devices in the treatment of unruptured distal anterior cerebral artery aneurysms.
Journal article
Salim HA. et al, (2026), Neurol Sci, 47
djunctive pharmacological strategies for residual risk reduction after myocardial revascularisation.
Journal article
Oshima A. et al, (2026), EuroIntervention, 22, 202 - 223
Metabolism in Tumour-Induced Bone Disease.
Journal article
Ormsby RT. and Edwards CM., (2026), Curr Osteoporos Rep, 24
ssessing the effects of a 3D pathology tissue-processing workflow on downstream molecular analyses.
Preprint
Baraznenok E. et al, (2026)
High-cholesterol diet fuels myeloma progression, dysregulates adipokine expression in vivo, and impairs treatment response ex vivo.
Journal article
Gámez B. et al, (2026), Haematologica
ctivity outcomes from past patients after total knee arthroplasty: regression tree analysis to generate insights for new patients
Conference paper
PINEDO VILLANUEVA R. et al, (2026)
People in Transplantation: Karin Hehenberger, MD, PhD.
Journal article
Issa F., (2026), Transplantation
Extracorporeal liver cross-circulation using transgenic xenogeneic pig livers with brain-dead human decedents.
Journal article
Shaked A. et al, (2026), Nat Med
The association between depot medroxyprogesterone acetate and meningiomas: Emerging data and their relevance to the South African context
Journal article
Burman RJ. et al, (2026), South African Medical Journal, 116
CAR-mediated release of IL-10 increases the function of regulatory T cells: relevance for future clinical application.
Journal article
Saleem A. et al, (2026), Mol Ther
Circulating TNFα in deceased donors promotes kidney injury and associates with inferior short- and long-term graft function and survival.
Journal article
Fawaz S. et al, (2026), Am J Transplant
Wnt-dependent spatiotemporal reprogramming of bone marrow niches drives fibrosis.
Journal article
Banjanin B. et al, (2026), Hemasphere, 10
Expanding the Therapeutic Horizon of Sodium Glucose Co-transporter-2 Inhibitors in Acute Kidney Injury.
Journal article
Dumbill R. and Zhu D., (2026), Transplantation, 110, e288 - e289
Brain Volumes After Hypertensive Pregnancy and Postpartum Blood Pressure Management: A POP-HT Randomized Clinical Trial Imaging Substudy.
Journal article
Lapidaire W. et al, (2026), JAMA Neurol, 83, 137 - 144
Lipoprotein(a) and Abdominal Aortic Aneurysm: A Genetically Verified Target Meets a Clinical Translational Window.
Journal article
Lee R., (2026), JACC Basic Transl Sci, 11
Scoping Review of the Photographic Assessment of Donor Liver Steatosis in Transplantation Using Artificial Intelligence.
Journal article
Kourounis G. et al, (2026), Clin Transplant, 40
Comparison of "Continuous" and "End-ischemic" Approaches of Oxygenated Hypothermic Machine Perfusion for Pancreas Preservation.
Journal article
Elzawahry MAME. et al, (2026), Transplant Direct, 12
Surgery in the Management of Recurrent Head and Neck Cancer.
Journal article
Williamson A. et al, (2026), Otolaryngol Clin North Am, 59, 181 - 197
ssessing the Clinical and Cost Effectiveness of Dialkylcarbamoylchloride (DACC) Coated Post-Operative Dressings Versus Standard Care in the Prevention of Surgical Site Infection in Clean or Clean-Contaminated, Vascular Surgery (DRESSINg Trial): Study Protocol for a Multicentre Randomised Controlled Trial
Journal article
Lim AJM. et al, (2026), International Wound Journal, 23
Safety and efficacy of microwave ablation of lung tumours close to the heart and aorta.
Journal article
Li Y-L. et al, (2026), Clin Radiol, 95
Neurosurgical management of paediatric central nervous system tumours in low, middle and high-income countries: a multi-centre, international, cross-sectional study.
Journal article
Bramer S. et al, (2026), Neurosurg Rev, 49
Past patients’ long-term experiences with complications, revision, and contralateral knee replacement after primary TKA can meaningfully inform the journey of new patients
Conference paper
PINEDO VILLANUEVA R. et al, (2026)
Harness Behavioural Analysis for Unpacking the Bio-Interpretability of Pathology Foundation Models
Preprint
Hu Y. et al, (2026)
Preoperative intentional weight loss to support postoperative recovery in patients with excess weight and colorectal cancer: the CARE feasibility randomised controlled trial
Journal article
Koutoukidis DA., (2026), Advances in Perioperative Care, 1
Genomic risk model to implement precision prostate cancer screening in clinical care: the ProGRESS study.
Journal article
Vassy JL. et al, (2026), Nat Cancer
Incidence of first and subsequent fractures in multiple myeloma patients: a parallel cohort study using UK CPRD dataset.
Journal article
Vijjhalwar R. et al, (2026), Osteoporos Int
Vascularised Composite Allotransplantation: Emerging Applications in Reconstructive Surgery and Solid Organ Transplantation.
Journal article
Hehir CM. et al, (2026), Medicina (Kaunas), 62
Professor Jeremy R. Chapman, AC: Editor-in-Chief, The Transplantation Journals.
Journal article
Issa F., (2026), Transplantation
Contrasting features of papillary and chromophobe renal cell carcinoma revealed by whole genome sequencing.
Journal article
Culliford R. et al, (2026), Mol Cancer Res
Circulating tumour cells as a window into lethality in prostate cancer.
Journal article
Abusamra SM. et al, (2026), Nat Rev Urol
Comparison of contrast-enhanced mammography and breast MRI in tumour extent assessment: A systematic review and meta-analysis.
Journal article
Ermans SJE. et al, (2026), Eur J Surg Oncol, 52
Urine Recirculation During Normothermic Kidney Preservation Improves Energy Balance Involving the Urea and TCA Cycles
Preprint
Weissenbacher A. et al, (2026)
Post-fracture care and predictors of anti-osteoporotic treatment in Switzerland: a nationwide health claims analysis.
Journal article
Everts-Graber J. et al, (2026), Osteoporos Int
Weight loss drugs are effective, but can healthcare systems afford them?
Journal article
West S. et al, (2026), BMJ, 392
Weight regain after cessation of medication for weight management: systematic review and meta-analysis.
Journal article
West S. et al, (2026), BMJ, 392
Integration of contraception provision in emergency obstetric and neonatal care: A scoping review.
Journal article
Koch MR. et al, (2026), Int J Gynaecol Obstet
Disease burden attributable to intimate partner violence against females and sexual violence against children in 204 countries and territories, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
Journal article
GBD 2023 Intimate Partner Violence and Sexual Violence against Children Collaborators ., (2026), Lancet, 407, 31 - 52
Letter to the editor: Precision-guided multi-site insular deep brain stimulation for refractory neuropathic pain.
Journal article
Segerdahl AR. et al, (2026), Brain Stimul, 19
Nicotinamide N-Methyl Transferase (NNMT) Sustains Innate Sensitivity to NAMPT Inhibition in YAP-dependent Stem-like/Mesenchymal Prostate Cancer.
Journal article
Carreira ÁSA. et al, (2026), Int J Biol Sci, 22, 1126 - 1141
Spatial fibroblast niches define Crohn's fistulae.
Journal article
McGregor C. et al, (2026), Nature, 649, 703 - 712
Development of a decision tree diagram for classifying study designs in tumour pathology research: a multidisciplinary approach.
Journal article
Craciun OM. et al, (2026), J Pathol Clin Res, 12
Unraveling and leveraging the molecular structural determinants of chemokine receptor-ligand specificity.
Journal article
Ho QY. and Issa F., (2026), Am J Transplant, 26, 2 - 3
Sigscores: summary scores for molecular signatures in R.
Journal article
Barberis A. and Buffa FM., (2026), Bioinform Adv, 6
Outcomes of Endoscopic Management of Spontaneous Cerebrospinal Fluid Rhinorrhea: A Meta-Analysis.
Journal article
Mughal Z. et al, (2026), Laryngoscope, 136, 36 - 49
Why academics should do more consulting - and how to make it work.
Journal article
Slater LJ. et al, (2026), Nature, 649, 27 - 29
ctDNA to Predict Treatment Response in Head and Neck Squamous Cell Carcinoma: A Systematic Review.
Journal article
Jones O. et al, (2026), Laryngoscope, 136, 50 - 62
Outcomes of Endoscopic Management of Spontaneous Cerebrospinal Fluid Rhinorrhea: A Meta-Analysis.
Journal article
Mughal Z. et al, (2026), Laryngoscope, 136, 36 - 49
Development of a decision tree diagram for classifying study designs in tumour pathology research: a multidisciplinary approach.
Journal article
Craciun OM. et al, (2026), J Pathol Clin Res, 12
Nicotinamide N-Methyl Transferase (NNMT) Sustains Innate Sensitivity to NAMPT Inhibition in YAP-dependent Stem-like/Mesenchymal Prostate Cancer.
Journal article
Carreira ÁSA. et al, (2026), Int J Biol Sci, 22, 1126 - 1141
Sir Roy Calne: a renaissance man of modern medicine
Journal article
Baquerizo A. et al, (2026), Frontiers in Transplantation, 4
Unsupervised Discovery of Spatiotypes and Context-Aware Graph Neural Networks for Modeling Clinical Endpoints
Chapter
Dawood M. et al, (2026), 15970 LNCS, 603 - 612
Diagnostic accuracy of a ‘stage-gated’ approach for reporting prostate screening MRI: “Is less more?”
Journal article
Thorley N. et al, (2026), European Radiology
Integrating multi-omic datasets investigating stress response biology decodes prostate cancer dynamic disease progression and places IRE1 activity at the epicentre of acquired treatment resistance
Journal article
Doultsinos D. et al, (2026), CANCER RESEARCH, 86
bstract PR013: Comprehensive spatial profiling of prostate cancer metastasis: Mapping clonal evolution, microenvironment dynamics, and early metastatic markers
Journal article
He M. et al, (2026), CANCER RESEARCH, 86, PR13 - PR13
How have systems approaches been used to understand how antimicrobials are used and governed in healthcare organisations? A scoping review protocol
Journal article
Lounsbury O. et al, (2026), Considerations in Medicine, 4, e000016 - e000016
Low Responsiveness of Macroencapsulated Human Islets Towards Glucose Challenge Despite Excellent Survival in Silicone-Based Oxygen-Delivering Devices.
Journal article
Brandhorst D. et al, (2025), Bioengineering (Basel), 13
Impact of preoperative weight-loss interventions on outcomes after elective non-bariatric surgery: meta-analysis.
Journal article
Wang D. et al, (2025), BJS Open, 10
Electrical Stimulation of Denervated Muscle: A Narrative Review.
Journal article
Chu L. et al, (2025), Artif Organs
Skin Cancer in Transplant Recipients: time to revisit immunosuppression trials?
Journal article
Bottomley MJ., (2025), Br J Dermatol
Surgery versus conservative management for severe pectus excavatum (RESTORE): protocol for a multicentre, randomised, controlled superiority trial.
Journal article
Maier R. et al, (2025), BMJ Open, 15
Redefining the topology of the human bone marrow using augmented spatial transcriptomic analysis
Preprint
Cooper RA. et al, (2025)
Leadership training in healthcare: a systematic umbrella review.
Journal article
Phillipson J. et al, (2025), BMJ Lead, 9, 349 - 359
Making evaluations useful for healthcare leadership development programmes.
Journal article
Lyons O. et al, (2025), BMJ Lead, 9, 421 - 427
Immune biomarkers for head and neck cancer.
Journal article
Sobhani N. et al, (2025), Cancer Immunol Immunother, 75
It never rains but pours: disseminated nocardiosis in a renal transplant patient from Nigeria - a case report.
Journal article
Whitehead T. et al, (2025), BMC Infect Dis, 26
What is the evidence base for leadership coaching for postgraduate medical doctors? A scoping review.
Journal article
Day FJ. et al, (2025), BMJ Lead
Knowledge, mobility and the built environment: assessing risk factors for road traffic incidents during children's school journeys in urban Blantyre, Malawi - an observational study.
Journal article
Nzanga M. et al, (2025), Inj Prev
Tandem Needle Technique Pleural Blood Patch Embolisation for Lung Ablations.
Journal article
Li Y-L. et al, (2025), Cardiovasc Intervent Radiol
Cost Effectiveness of Local Anaesthetic Transperineal Versus Transrectal Biopsy: Results from the TRANSLATE Study.
Journal article
Little M. et al, (2025), Eur Urol Focus
Novel drinkable oxygen nanobubbles: A pilot randomised, double-blind, cross-over trial on Pulmonary Fibrosis patients
Journal article
SHETH M. and STRIDE E., (2025), BMJ Innovations
ificial Intelligence Based Mobile Health Applications for Patients with Abdominal Aortic Aneurysms and Peripheral Arterial Disease: Patients' and Healthcare Workers' Attitudes.
Journal article
Zwetsloot SL. et al, (2025), Eur J Vasc Endovasc Surg
Correction: Spatial fibroblast niches define Crohn's fistulae.
Journal article
McGregor C. et al, (2025), Nature, 648
Preoperative Weight Loss in Patients With Excess Weight and Colorectal Cancer: The CARE Feasibility Randomized Clinical Trial.
Journal article
Koutoukidis DA. et al, (2025), JAMA Netw Open, 8
British Skull Base Society Consensus on Vestibular Schwannoma Surveillance.
Journal article
Sethi M. et al, (2025), J Neurol Surg B Skull Base, 86, 619 - 625
ctive Monitoring, Surgery, and Radiotherapy for Cribriform-Positive and Cribriform-Negative Prostate Cancer: A Secondary Analysis of the PROTECT Randomized Clinical Trial.
Journal article
Sushentsev N. et al, (2025), JAMA Oncol, 11, 1512 - 1517
Emerging strategies in the transplantation of HCV-infected pancreases to uninfected recipients: A narrative review.
Journal article
Bush AJ. et al, (2025), Transplant Rev (Orlando), 39
Global, regional, and national burden of headache disorders, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023.
Journal article
GBD 2023 Headache Collaborators ., (2025), Lancet Neurol, 24, 1005 - 1015
Propensity-matched analysis of the impact of saphenous vein graft external stenting on clinical outcomes in coronary bypass surgery: The RESTART study.
Journal article
Weltert LP. et al, (2025), JTCVS Open, 28, 214 - 226
Quantifying the health-care burden of temperature in the National Health Service in England: an economic analysis of resource use and costs.
Journal article
Fahr P. et al, (2025), Lancet Planet Health, 9
Improving Access to Pediatric Surgery in LMICs Through Capacity-Building: A Systematic Review.
Journal article
Malik M. et al, (2025), Pediatrics, 156
Improving outcomes in kidney transplantation through advances in donor organ perfusion.
Journal article
Hunter J. et al, (2025), Nat Rev Nephrol, 21, 818 - 832
Early Activation of the Complement System After Brain Death in Clinical Kidney Donation and Transplantation.
Journal article
Knijff LWD. et al, (2025), Transplantation, 109, 1845 - 1854
Prediction of Pathological Subthalamic Nucleus Beta Burst Occurrence in Parkinson's Disease.
Journal article
Abdi-Sargezeh B. et al, (2025), Mov Disord, 40, 2615 - 2627
Non-invasive ultrasonic neuromodulation of the human nucleus accumbens impacts reward sensitivity.
Journal article
Yaakub SN. et al, (2025), Nat Commun, 16
Intravenous Thrombolysis in Distal Medium Middle Cerebral Artery Occlusion Patients with Unsuccessful Mechanical Reperfusion.
Journal article
Salim HA. et al, (2025), Clin Neuroradiol
Radial Artery Embolization to the Intracranial Circulation as a Complication of Percutaneous Coronary Intervention.
Journal article
Neuhaus A. et al, (2025), JACC Cardiovasc Interv, 18, 2823 - 2826
Development of a PRISMA extension for systematic reviews of health economic evaluations (PRISMA-EconEval): a project protocol.
Journal article
Tran PB. et al, (2025), Syst Rev, 14
Global research partnerships and the impact of inequitable research practices on systematic reviews.
Journal article
Kinyanjui LW. et al, (2025), BMJ Glob Health, 10
Translational Potential of an Electrospun Polycaprolactone Scaffold for Anterior Cruciate Ligament Reconstruction.
Journal article
Lin J. et al, (2025), Adv Fiber Mater
Predictive modeling of long-term improvement in occlusion outcomes following Woven EndoBridge treatment of cerebral aneurysms: A machine learning approach.
Journal article
Karandish A. et al, (2025), Interv Neuroradiol
IGF-1 regulates cancer cell immune evasion in prostate cancer.
Journal article
Nandakumar AM. et al, (2025), Sci Rep, 15
The latent system factors that influence antimicrobial use and governance in healthcare: a scoping review of high-income health systems.
Journal article
Lounsbury O. et al, (2025), EClinicalMedicine, 89
Islet autotransplantation after pancreatic resection for focal intraductal papillary mucinous neoplasm: A step too far?
Journal article
Pandanaboyana S. et al, (2025), Am J Transplant, 25, 2469 - 2470
Exploring patient and clinician opinions, perspectives and acceptance of the use of artificial intelligence in the histological diagnosis of prostate cancer.
Journal article
Browning L. et al, (2025), BJUI Compass, 6
Comparative Performance of Clinician and Computational Approaches in Forecasting Adverse Outcomes in Intermittent Claudication.
Journal article
Ravindhran B. et al, (2025), Ann Vasc Surg, 120, 138 - 145
The impact of socioeconomic status on the management of epilepsy: a qualitative study.
Journal article
Spooner J. et al, (2025), Epilepsy Behav, 172
Impact of Blood Pressure Self-Management on Vascular Remodeling After Hypertensive Pregnancy.
Journal article
Kitt J. et al, (2025), Hypertension, 82, 1938 - 1947
Kidney stone disease: risk factors, pathophysiology and management.
Journal article
Bargagli M. et al, (2025), Nat Rev Nephrol, 21, 794 - 808
Multidisciplinary evidence-based consensus statements on salvage surgery for recurrent head and neck cancer (International Centre for Recurrent Head and Neck Cancer).
Journal article
Williamson A. et al, (2025), J Natl Cancer Inst, 117, 2202 - 2218
Comparative Performance of Clinician and Computational Approaches in Forecasting Adverse Outcomes in Intermittent Claudication.
Journal article
Ravindhran B. et al, (2025), Ann Vasc Surg, 120, 138 - 145
The development of a data dictionary with clinical variables for artificial intelligence-driven tools in research on abdominal aortic aneurysms and peripheral arterial disease
Journal article
Rijken L. et al, (2025), European Heart Journal Digital Health, 6, 1104 - 1112
Comprehensive proteome profiling of cytochrome P450 isoforms in cancer models.
Journal article
Shaheed SU. et al, (2025), Clin Proteomics, 22
Single-cell analysis uncovers preserved prostate cancer lineages and universally altered pathways in Matrigel-free patient-derived organoids.
Journal article
Dolgos R. et al, (2025), Cell Rep, 44
International survey-based assessment of the reliability, validity, and interpretability of the TDN grade for neurosurgical adverse events.
Journal article
Terrapon APR. et al, (2025), Sci Rep, 15
ssociation between hyperglycaemia, diabetes complications and development of fibrotic conditions among people living with type 1 and type 2 diabetes in England: a retrospective cohort study using UK Clinical Resource Datalink Aurum and Hospital Episode Statistics.
Journal article
Massen GM. et al, (2025), BMJ Open, 15
Lessons learned from a multi-centre implementation of an artificial intelligence algorithm to detect vertebral fractures for radiology, information technology, information governance and clinical leads
Journal article
Vijjhalwar R. et al, (2025), BJR Artificial Intelligence, 2
Global, regional, and national burden of headache disorders, 1990-2021, with forecasts to 2050: A Global Burden of Disease study 2021.
Journal article
GBD 2021 Headache Collaborators. Electronic address: yonkkang@gmail.com . et al, (2025), Cell Rep Med, 6
ificial Intelligence and Machine Learning for Risk Prediction of Abdominal Aortic Aneurysm Growth and Rupture.
Journal article
Guo J. et al, (2025), Angiology
Prepectoral no mesh versus mesh immediate implant-based reconstruction after mastectomy (Restore-B): a multicentre single-blinded randomised controlled feasibility study protocol.
Journal article
Rolph R. et al, (2025), BMJ Open, 15
Fibroblast specialisation across microanatomy in a single-cell atlas of healthy human Achilles tendon
Preprint
Cohen CJ. et al, (2025)
HLA matching or CRISPR editing of HLA class I/II enables engraftment and effective function of allogeneic human regulatory T cell therapy in a humanized mouse transplantation model.
Journal article
McCallion O. et al, (2025), Nat Commun, 16
RWD89 Hospital Resource Utilization and Costs of Imminent Subsequent Fractures in Postmenopausal Women: A Distributed Network Analysis Using Data From the UK and Spain Mapped to OMOP Common Data Model
Conference paper
Fabiano G. et al, (2025), Value in Health, s590 - s590
Using optical skyrmions to assess vectorial adaptive optics capabilities in the presence of complex aberrations.
Journal article
Ma Y. et al, (2025), Sci Adv, 11
Ventromedial prefrontal cortex lesions disrupt learning to reward others.
Journal article
Gueguen M. et al, (2025), Brain, 148, 3537 - 3550
clinical investigation of a new gelling fibre dressing containing silver for the management of partial-thickness burns.
Journal article
Lewis CJ. et al, (2025), J Wound Care, 34, 797 - 804
Getting recovery right after neck dissection for head and neck cancer (GRRAND): trial protocol for a multicentre, pragmatic randomised controlled trial with health economic evaluation and process evaluation.
Journal article
Evans C. et al, (2025), BMJ Open, 15
What spatial omics is teaching us about field cancerisation in prostate and bladder cancer.
Journal article
Byrne MHV. et al, (2025), BJU Int, 136, 578 - 589
Renal resistance trajectories during hypothermic machine perfusion in kidneys donated after circulatory death: Associations with donor characteristics and posttransplant outcomes-An analysis of COMPARE trial data.
Journal article
Verstraeten L. et al, (2025), Am J Transplant, 25, 2161 - 2172
Distinct Cytokine Responses in Central and Systemic Compartments after Subarachnoid Haemorrhage.
Journal article
Bandyopadhyay S. et al, (2025), Transl Stroke Res, 16, 1766 - 1782
What spatial omics is teaching us about field cancerisation in prostate and bladder cancer.
Journal article
Byrne MHV. et al, (2025), BJU Int, 136, 578 - 589
Detection of Genome-Wide IGF-1R Recruitment to Enhancer and Promoter Regions of Chromatin in Clinical Prostate Cancers.
Journal article
Mills JV. et al, (2025), Cancer Med, 14
Understanding structured medication reviews delivered by clinical pharmacists in primary care in England: a national cross-sectional survey.
Journal article
Agwunobi AJ. et al, (2025), BMJ Open, 15
Core Outcome Set for Patients with Chronic Symptomatic Peripheral Arterial Disease.
Journal article
Zwetsloot SLM. et al, (2025), Eur J Vasc Endovasc Surg
Sexual misconduct: UK medical practitioners tribunal service is not fit to practise.
Journal article
Dixon F. et al, (2025), BMJ, 390
The societal implications of using glucagon-like peptide-1 receptor agonists for the treatment of obesity.
Journal article
Scragg J. et al, (2025), Med, 6
Belantamab Mafodotin Triggers Immune Invigoration in Multiple Myeloma Via Inflammatory and Immunogenic Cell Death
Preprint
Watson ECR. et al, (2025)
journey of leading a healthcare start-up in India: from the National Health Service to a corporate leadership culture.
Journal article
Kalra GS. et al, (2025), BMJ Lead
Circulating tumour DNA to augment PET-CT in determining clinical outcome after head and neck cancer treatment.
Journal article
Bola S. et al, (2025), Eur J Cancer, 227
Design, synthesis and characterization of aryl bis-guanyl hydrazones as RNA binders of C9orf72 G4C2 extended repeats.
Journal article
Maiocchi A. et al, (2025), Eur J Med Chem, 293
Dietary-dependent sensitization of neuronal leptin signaling promotes neural repair after injury via cAMP and gene transcription.
Journal article
Chadwick JS. et al, (2025), Neuron, 113, 2839 - 2855.e8
The NEON (Nerve rEpair Or Not) trial: a randomized controlled trial of microsurgical repair versus nerve alignment for digital nerve injury.
Journal article
Wormald JCR. et al, (2025), Br J Surg, 112
Innovations and strategies for effective implementation of post pregnancy contraception services: Learnings from the FIGO PPIUD initiative.
Journal article
Makins A. et al, (2025), Best Pract Res Clin Obstet Gynaecol, 102
The hormonal nexus in PIK3CA-mutated meningiomas: implications for targeted therapy and clinical trial design.
Journal article
Abikenari M. et al, (2025), J Neurooncol, 174, 329 - 340
Evaluation of a national digital pre-implantation biopsy service for deceased-donor kidney transplantation in the UK (Pithia trial); a stepped-wedge cluster randomised registry trial.
Journal article
Summers DM. et al, (2025), Lancet Reg Health Eur, 56
F4/80, the plasma membrane antigen of mouse macrophages, an historic journey.
Journal article
Gordon S. et al, (2025), J Leukoc Biol, 117
Best practices of heart transplantation in mice.
Journal article
Alegre M-L. et al, (2025), Am J Transplant, 25, 1820 - 1829
Reverse innovation - South to North learnings in the provision of postpartum contraception: implementation in a high-income setting.
Journal article
Makins A. et al, (2025), Best Pract Res Clin Obstet Gynaecol, 102
SegMorph: Concurrent Motion Estimation and Segmentation for Cardiac MRI Sequences.
Journal article
Bi N. et al, (2025), IEEE Trans Med Imaging, 44, 3515 - 3528
Designing better systems to navigate the sepsis-antimicrobial stewardship tension.
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Participants to the Global Summit in Transplantation, organized by the Organización Nacional de Trasplantes under the Spanish Presidency of the Council of the European Union, the European Directorate for the Quality of Medicines and Healthcare−Council of Europe, the European Society for Organ Transplantation, and The Transplantation Society, co-sponsored by the World Health Organization and supported by the International Society of Nephrology in Santander, Spain, November 9 and 10, 2023 ., (2025), Transplantation, 109, 7 - 9
Finite Element Modelling for Biophysical Models of Nervous System Stimulation: Best Practices for Multiscale Adaptive Meshing.
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L R. et al, (2025), IEEE Trans Neural Syst Rehabil Eng, 33, 298 - 309
Vascularised Composite Allotransplantation - A guide to optimal dissemination of scientific outputs.
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Hehir CM. et al, (2025), J Hand Microsurg, 17
Communication Between Anaesthesia Providers for Clinical and Professional Purposes: A Scoping Review.
Journal article
Edgcombe H. et al, (2025), Anesthesiol Res Pract, 2025
Clinical Implications of Basic Research: Exploring the Transformative Potential of Spatial 'Omics in Uro-oncology.
Journal article
Figiel S. et al, (2025), Eur Urol, 87, 8 - 14
Pancreas Preservation: Hypothermic Oxygenated Perfusion to Improve Graft Reperfusion.
Journal article
Mesnard B. et al, (2025), Transplantation, 109, e1 - e10
Retraction notice to "Effects of environmental impact and nutrition labelling on food purchasing: An experimental online supermarket study" [Appetite 180 (2023) 106312].
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Potter C. et al, (2025), Appetite, 205
Trends and health equity in environmental sustainability publications in major anaesthesia journals.
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Fabus MS. and Kudsk-Iversen S., (2025), Anaesthesia, 80, 115 - 116
Clonal phylogenies inferred from bulk, single cell, and spatial transcriptomic analysis of epithelial cancers.
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Erickson A. et al, (2025), PLoS One, 20
Finite Element Modelling for Biophysical Models of Nervous System Stimulation: Best Practices for Multiscale Adaptive Meshing.
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L R. et al, (2025), IEEE Trans Neural Syst Rehabil Eng, 33, 298 - 309
Urinary continence networks in Parkinson's disease: a resting state functional MRI study.
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Roy HA. et al, (2025), BJU Int, 135, 57 - 59
Communication Between Anaesthesia Providers for Clinical and Professional Purposes: A Scoping Review.
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Edgcombe H. et al, (2025), Anesthesiol Res Pract, 2025
The use of healthcare simulation to identify and address latent safety threats: a scoping review.
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Lounsbury O. et al, (2025), Front Health Serv, 5
'No-touch' or 'soft-touch' vein graft harvesting for CABG.
Journal article
Taggart DP., (2025), Indian J Thorac Cardiovasc Surg, 41, 4 - 6
Vascularised Composite Allotransplantation - A guide to optimal dissemination of scientific outputs.
Journal article
Hehir CM. et al, (2025), J Hand Microsurg, 17
Clinical Implications of Basic Research: Exploring the Transformative Potential of Spatial 'Omics in Uro-oncology.
Journal article
Figiel S. et al, (2025), Eur Urol, 87, 8 - 14
Entering the era of spatial transcriptomics: opportunities and challenges for pathology
Journal article
Sozanska AM. et al, (2025), Diagnostic Histopathology
Trusted Friend in the Middle of the Night: End-User Perspectives on Artificial Intelligence Informed Software Systems as a Decision-Making Aid for Patients and Clinicians Navigating Uncertainty in Kidney Transplant
Chapter
Wingfield LR. et al, (2025), 15383 LNCS, 193 - 209
Statistical Methods in Childhood Cancer Research
Chapter
Bandyopadhyay S. and Lakhoo K., (2025), 725 - 737
PET–CT Surveillance versus Neck Dissection in Advanced Head and Neck Cancer
Chapter
Ishii H. and Winter S., (2025), 8 - 14
General principles of organ preservation in liver transplantation
Chapter
Abbas SH. et al, (2025), 247 - 268
Maximizing the Impact of the FRAM: From Analysis to Implementation
Chapter
Sujan M. and Lounsbury O., (2025), 389 - 406
Entering the era of spatial transcriptomics: opportunities and challenges for pathology
Journal article
Sozanska AM. et al, (2025), Diagnostic Histopathology
pplying Fluid-Walled Microfluidic Technology to Investigate the Niche Tumor Bone Microenvironment in ProstateCancer Bone Metastasis
Conference paper
Aleezada Z. et al, (2025), SOUTHERN MEDICAL JOURNAL, 118
Clinical and health economic benefits of AI-enabled vertebral fracture (VF) identification for Fracture Liaison Services (FLSs): the UK Adopt Study
Conference paper
Javaid MK. et al, (2025), JOURNAL OF BONE AND MINERAL RESEARCH, 40
PATIENT-DERIVED RENAL CELL CANCER ORGANOIDS AS A MODEL TO ASSESS THERAPEUTIC TARGETS AND TREATMENT RESISTANCE MECHANISMS
Conference paper
Daniel AT. et al, (2025), UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS, 43
VALIDATION OF PRIMARY CARE RESOURCE USE AND COSTS IN OMOP-MAPPED VS. SOURCE CPRD AURUM DATA
Conference paper
Fabiano G. et al, (2025), VALUE IN HEALTH, 28
Proteomic risk factors for prostate cancer: A case-cohort study in EPIC
Journal article
Huang Z. et al, (2025), CANCER RESEARCH, 85
N EVALUATION OF THE IMPLEMENTATION OF A NOVEL DIGITAL INTERVENTION FOR HYPERTENSION MANAGEMENT: THE SHIP STUDY
Conference paper
McManus R. et al, (2025), JOURNAL OF HYPERTENSION, 43
n Integrated Spatial and Single-Cell Multiomics Platform for Translational Research in Multiple Myeloma
Conference paper
Gooding S. et al, (2025), CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 25
Nitric oxide treatment during normothermic perfusion of the kidney - a pre-clinical study
Journal article
Dumbill R. et al, (2025), BJS-BRITISH JOURNAL OF SURGERY, 112
Prospective and genetic analyses implicate lower immunosurveillance in the aetiology of prostate cancer
Journal article
Parsaeian M. et al, (2025), CANCER RESEARCH, 85
Effectiveness of hypothermic machine perfusion and static cold storage as delivery methods of a novel RIPK1 inhibitor into pig kidneys and its effects on ischaemia-reperfusion injury
Journal article
Mellati A. et al, (2025), BJS-BRITISH JOURNAL OF SURGERY, 112, 10 - 10
USING A TRANSIENT COLD ROOM DURING COBE ISLET PURIFICATION REDUCES THE ENVIRONMENTAL MICROBIAL BURDEN AND ASSOCIATED ENERGY COSTS WHEN COMPARED TO THE USE OF A PERMANENT COLD ROOM
Journal article
Crawford L. et al, (2025), TRANSPLANTATION, 109, 86 - 86
EFFECTIVENESS OF A NOVEL DIGITAL INTERVENTION IN REDUCING HOME BLOOD PRESSURE IN HYPERTENSIVE PATIENTS: INSIGHTS FROM A REAL-WORLD OBSERVATIONAL STUDY
Conference paper
Fujiwara T. et al, (2025), JOURNAL OF HYPERTENSION, 43
Volumetric analysis of spatial tumor phylogeny enabled by 3D pathology-guided macrodissection (3DPM)
Journal article
Hsieh H-C. et al, (2025), CANCER RESEARCH, 85
The COAST (Contemporary Outcomes After cutaneous SCC in Transplant recipients) study: final results and implications for management following the first cutaneous squamous cell carcinoma in kidney transplant recipients
Journal article
Peleva E. et al, (2025), BRITISH JOURNAL OF DERMATOLOGY, 193
Metabolomic Signatures of Perfused Livers Reveal Early Evaluation May Be Superior
Conference paper
Fortier A. et al, (2025), AMERICAN JOURNAL OF TRANSPLANTATION, 25, s29 - s29
Characterising Prognostic Complement Biomarkers during Clinical Normothermic Machine Perfusion for Renal Transplantation
Conference paper
Fallon JI. et al, (2025), AMERICAN JOURNAL OF TRANSPLANTATION, 25, S151 - S151
Targeting TNFα signalling in deceased donor kidneys: a path to improve graft outcomes
Journal article
Fawaz S. et al, (2025), NEPHROLOGY DIALYSIS TRANSPLANTATION, 40
Osteoporosis Treatment Rates Following Hip, Spine, and Other Fractures in Older Adults in Switzerland: Insights from National Health Claims Data (2021-2023)
Conference paper
Everts-Graber J. et al, (2025), SWISS MEDICAL WEEKLY, 155
The COAST (Contemporary Outcomes After cutaneous SCC in Transplant recipients) study: final results and implications for management following the first cutaneous squamous cell carcinoma in kidney transplant recipients
Journal article
Peleva E. et al, (2025), BRITISH JOURNAL OF DERMATOLOGY, 193
Volumetric analysis of spatial tumor phylogeny enabled by 3D pathology-guided macrodissection (3DPM)
Journal article
Hsieh H-C. et al, (2025), CANCER RESEARCH, 85
pplying Fluid-Walled Microfluidic Technology to Investigate the Niche Tumor Bone Microenvironment in ProstateCancer Bone Metastasis
Conference paper
Aleezada Z. et al, (2025), SOUTHERN MEDICAL JOURNAL, 118
Nitric oxide treatment during normothermic perfusion of the kidney - a pre-clinical study
Journal article
Dumbill R. et al, (2025), BJS-BRITISH JOURNAL OF SURGERY, 112
Characterising Prognostic Complement Biomarkers during Clinical Normothermic Machine Perfusion for Renal Transplantation
Conference paper
Fallon JI. et al, (2025), AMERICAN JOURNAL OF TRANSPLANTATION, 25, S151 - S151
Prospective and genetic analyses implicate lower immunosurveillance in the aetiology of prostate cancer
Journal article
Parsaeian M. et al, (2025), CANCER RESEARCH, 85
Prolonged functional warm ischaemia is associated with metabolic and protease dysregulation in DCD kidneys
Journal article
Vaughan R. et al, (2025), NEPHROLOGY DIALYSIS TRANSPLANTATION, 40
Stress-Induced Rab11a-Exosomes Induce Amphiregulin-Mediated Cetuximab Resistance in Colorectal Cancer (vol 13, e12465, 2024)
Journal article
Mason JD. et al, (2025), JOURNAL OF EXTRACELLULAR VESICLES, 14
Mapping clonal heterogeneity and stromal dynamics in prostate cancer
Journal article
Figiel S. et al, (2025), CANCER RESEARCH, 85
Plasma uromodulin dynamics in deceased kidney donors and the association with transplant outcomes
Journal article
Michelakis I. et al, (2025), NEPHROLOGY DIALYSIS TRANSPLANTATION, 40
Can Pretransplant Donor Cystatin-C Identify High-Risk Kidneys? Insights into Grafts with Primary Non-Function and Long-Term Transplant Outcomes
Conference paper
Michelakis IE. et al, (2025), AMERICAN JOURNAL OF TRANSPLANTATION, 25
PKCδ Neurons in the Bed Nucleus of the Stria Terminalis Exhibit Dysregulated Activity following Chronic Ethanol Exposure
Journal article
Doyle M. et al, (2025), JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 392
Plasma Uromodulin Dynamics in Deceased Donors: A Marker of Tubular Integrity for Post-Transplant Kidney Function
Conference paper
Michelakis IE. et al, (2025), AMERICAN JOURNAL OF TRANSPLANTATION, 25
IMPACT OF AI-ENABLED VERTEBRAL FRACTURE (VF) IDENTIFICATION ON FRACTURE LIAISON SERVICE (FLS) KEY PERFORMANCE INDICATORS (KPIS) AND TREATMENT RECOMMENDATIONS VARIES BY FLS
Conference paper
Clemeno FAA. et al, (2025), AGING CLINICAL AND EXPERIMENTAL RESEARCH, 37, 9 - 9
N ARTIFICIAL INTELLIGENCE ALGORITHM TO IMPROVE DIAGNOSIS OF VERTEBRAL FRACTURES EMBEDDED IN FRACTURE LIAISON SERVICES CAN REDUCE FRACTURES AND REDUCE COSTS
Conference paper
Pinedo-Villanueva R. et al, (2025), AGING CLINICAL AND EXPERIMENTAL RESEARCH, 37, 56 - 57
MICROPARTICLES TO IMPROVE ISLET TRANSPLANTATION OUTCOMES IN AN EX-VIVO PORCINE LIVER MODEL FOR TYPE 1 DIABETES
Journal article
Giai VF. et al, (2025), TRANSPLANTATION, 109, 90 - 90
n Integrated Spatial and Single-Cell Multiomics Platform for Translational Research in Multiple Myeloma
Conference paper
Gooding S. et al, (2025), CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 25
EFFECTIVENESS OF A NOVEL DIGITAL INTERVENTION IN REDUCING HOME BLOOD PRESSURE IN HYPERTENSIVE PATIENTS: INSIGHTS FROM A REAL-WORLD OBSERVATIONAL STUDY
Conference paper
Fujiwara T. et al, (2025), JOURNAL OF HYPERTENSION, 43
DISTINCT CLUSTERS OF CARERS WITH X-LINKED HYPOPHOSPHATAEMIA BASED ON THEIR QUALITY OF LIFE
Conference paper
Njuki N. et al, (2025), AGING CLINICAL AND EXPERIMENTAL RESEARCH, 37, 617 - 617
IMPACT OF AI-ENABLED VERTEBRAL FRACTURE (VF) IDENTIFICATION ON FRACTURE LIAISON SERVICE (FLS) KEY PERFORMANCE INDICATORS (KPIS) AND TREATMENT RECOMMENDATIONS VARIES BY FLS
Conference paper
Clemeno FAA. et al, (2025), AGING CLINICAL AND EXPERIMENTAL RESEARCH, 37, 470 - 470
Recent publications
TCR T cells targeting IgA- and IgG-expressing multiple myeloma.
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Douvlataniotis K. et al, (2026), Blood
Vortex-actuated pre-enrichment accelerates human regulatory T cell sorting and improves early fitness
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Ho QY. et al, (2026), Molecular Therapy Advances, 34, 201667 - 201667
People in Transplantation: Karin Hehenberger, MD, PhD.
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Issa F., (2026), Transplantation
CAR-mediated release of IL-10 increases the function of regulatory T cells: relevance for future clinical application.
Journal article
Saleem A. et al, (2026), Mol Ther
Professor Jeremy R. Chapman, AC: Editor-in-Chief, The Transplantation Journals.
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Issa F., (2026), Transplantation
Unraveling and leveraging the molecular structural determinants of chemokine receptor-ligand specificity.
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Ho QY. and Issa F., (2026), Am J Transplant, 26, 2 - 3
Redefining the topology of the human bone marrow using augmented spatial transcriptomic analysis
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Cooper RA. et al, (2025)
HLA matching or CRISPR editing of HLA class I/II enables engraftment and effective function of allogeneic human regulatory T cell therapy in a humanized mouse transplantation model.
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McCallion O. et al, (2025), Nat Commun, 16
clinical investigation of a new gelling fibre dressing containing silver for the management of partial-thickness burns.
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Lewis CJ. et al, (2025), J Wound Care, 34, 797 - 804
Belantamab Mafodotin Triggers Immune Invigoration in Multiple Myeloma Via Inflammatory and Immunogenic Cell Death
Preprint
Watson ECR. et al, (2025)